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Loss of Notch signaling in skeletal stem cells enhances bone formation with aging

Lindsey H.Remark Kevin Leclerc Malissa Ramsukh Ziyan Lin Sooyeon Lee Backialakshmi Dharmalingam Lauren Gillinov Vasudev V.Nayak Paulo El Parente Margaux Sambon Pablo J.Atria Mohamed A.E.Ali Lukasz Witek Alesha B.Castillo Christopher Y.Park Ralf H.Adams Aristotelis Tsirigos Sophie M.Morgani Philipp Leucht

Bone Research2023,Vol.11Issue(4):P.737-750,14.
Bone Research2023,Vol.11Issue(4):P.737-750,14.DOI:10.1038/s41413-023-00283-8

Loss of Notch signaling in skeletal stem cells enhances bone formation with aging

Lindsey H.Remark 1Kevin Leclerc 1Malissa Ramsukh 1Ziyan Lin 2Sooyeon Lee 3Backialakshmi Dharmalingam 4Lauren Gillinov 1Vasudev V.Nayak 5Paulo El Parente 1Margaux Sambon 1Pablo J.Atria 1Mohamed A.E.Ali 6Lukasz Witek 7Alesha B.Castillo 1Christopher Y.Park 6Ralf H.Adams 4Aristotelis Tsirigos 2Sophie M.Morgani 1Philipp Leucht8

作者信息

  • 1. Department of Orthopaedic Surgery,NYU Robert I.Grossman School of Medicine,New York,NY,USA
  • 2. Applied Bioinformatics Laboratories,NYU Grossman School of Medicine,New York,NY,USA
  • 3. Department of Orthopaedic Surgery,NYU Robert I.Grossman School of Medicine,New York,NY,USA Institute of Comparative Molecular Endocrinology,Ulm University,Ulm,Germany
  • 4. Max Planck Institute for Molecular Biomedicine,Department of Tissue Morphogenesis,and University of Münster,Faculty of Medicine,D-48149 Münster,Germany
  • 5. Department of Biochemistry and Molecular Biology,University of Miami Miller School of Medicine,Miami,FL,USA
  • 6. Department of Pathology,NYU Robert I.Grossman School of Medicine,New York,NY,USA
  • 7. Biomaterials Division,New York University College of Dentistry,New York,NY,USA Hansjörg Wyss Department of Plastic Surgery,NYU Grossman School of Medicine,New York University,New York,NY,USA Department of Biomedical Engineering,Tandon School of Engineering,New York University,Brooklyn,NY,USA
  • 8. Department of Orthopaedic Surgery,NYU Robert I.Grossman School of Medicine,New York,NY,USA Department of Cell Biology,NYU Robert I.Grossman School of Medicine,New York,NY,USA
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摘要

关键词

Notch/skeletal/elevated

分类

医药卫生

引用本文复制引用

Lindsey H.Remark,Kevin Leclerc,Malissa Ramsukh,Ziyan Lin,Sooyeon Lee,Backialakshmi Dharmalingam,Lauren Gillinov,Vasudev V.Nayak,Paulo El Parente,Margaux Sambon,Pablo J.Atria,Mohamed A.E.Ali,Lukasz Witek,Alesha B.Castillo,Christopher Y.Park,Ralf H.Adams,Aristotelis Tsirigos,Sophie M.Morgani,Philipp Leucht..Loss of Notch signaling in skeletal stem cells enhances bone formation with aging[J].Bone Research,2023,11(4):P.737-750,14.

基金项目

supported by a K08AR069099 (P.L.) from the National Institutes of Health/ National Institute of Arthritis and Musculoskeletal and Skin (P.L.)

supported by an R01AG056169 and a gift by the Patricia and Frank Zarb Family ()

supported by an F30AG072834 from the National Institutes of Health/National Institute on Aging ()

funded through NIH Grant S10OD010751 and the Preclinical Imaging Laboratory ()

partially supported by the Laura and Isaac Perlmutter Cancer Center Support Grant NIH/NCI 5P30CA016087 ()

NIBIB Biomedical Technology Resource Center Grant NIH P41 EB017183 ()

supported in part by grant P30CA016087 from the National Institutes of Health/National Cancer Institute ()

partially supported by the Cancer Center Support Grant P30CA016087 at the Laura and Isaac Perlmutter Cancer Center。 ()

Bone Research

OACSCDMEDLINE

2095-4700

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