首页|期刊导航|Bone Research|Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling

Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling

Ri-Xu Liu Rong-He Gu Zhi-Peng Li Zhi-Quan Hao Qin-Xiao Hu Zhen-Yan Li Xiao-Gang Wang Wang Tang Xiao-He Wang Yu-Kai Zeng Zhen-Wei Li Qiu Dong Xiao-Feng Zhu Di Chen Ke-Wei Zhao Rong-Hua Zhang Zhen-Gang Zha Huan-Tian Zhang

Bone Research2023，Vol.11Issue(4)：P.819-833,15.

Bone Research2023，Vol.11Issue(4)：P.819-833,15.DOI:10.1038/s41413-023-00296-3

Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling

Ri-Xu Liu ¹Rong-He Gu ²Zhi-Peng Li ³Zhi-Quan Hao ³Qin-Xiao Hu ³Zhen-Yan Li ³Xiao-Gang Wang ⁴Wang Tang ³Xiao-He Wang ³Yu-Kai Zeng ³Zhen-Wei Li ³Qiu Dong ³Xiao-Feng Zhu ⁵Di Chen ⁶Ke-Wei Zhao ⁷Rong-Hua Zhang ³Zhen-Gang Zha ³Huan-Tian Zhang³

作者信息

1. Department of Bone and Joint Surgery,the First Affiliated Hospital of Jinan University,Key Laboratory of Regenerative Medicine of Ministry of Education,Jinan University,Guangzhou 510630 Guangdong,China Department of Orthopedic and Spine Surgery,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120 Guangdong,China
2. School of Basic Medical Sciences of Guangxi Medical University,the Fifth Affiliated Hospital of Guangxi Medical University,Nanning 530022 Guangxi,China
3. Department of Bone and Joint Surgery,the First Affiliated Hospital of Jinan University,Key Laboratory of Regenerative Medicine of Ministry of Education,Jinan University,Guangzhou 510630 Guangdong,China
4. Key Laboratory of Big Data-Based Precision Medicine,School of Engineering Medicine,Beihang University,100191 Beijing,China
5. Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Informatization,College of Pharmacy,Jinan University,Guangzhou 510630 Guangdong,China
6. Research Center for Computer-aided Drug Discovery,Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,518005 Shenzhen,China
7. Guangzhou Key Laboratory of Chinese Medicine Research on Prevention and Treatment of Osteoporosis,the Third Affiliated Hospital of Guangzhou University of Chinese Medicine,510375 Guangzhou,China
折叠

摘要

关键词

YAP1/osteoporosis/depletion

分类

医药卫生

引用本文复制引用

Ri-Xu Liu,Rong-He Gu,Zhi-Peng Li,Zhi-Quan Hao,Qin-Xiao Hu,Zhen-Yan Li,Xiao-Gang Wang,Wang Tang,Xiao-He Wang,Yu-Kai Zeng,Zhen-Wei Li,Qiu Dong,Xiao-Feng Zhu,Di Chen,Ke-Wei Zhao,Rong-Hua Zhang,Zhen-Gang Zha,Huan-Tian Zhang..Trim21 depletion alleviates bone loss in osteoporosis via activation of YAP1/β-catenin signaling[J].Bone Research,2023,11(4):P.819-833,15.

基金项目

supported by the Natural Science Foundation with grants from the National Key R&D Program of China(2018YFC2002500) （2018YFC2002500）

National Natural Science Foundation of China(81602360,82072470,82350003,92049201) （81602360,82072470,82350003,92049201）

Key Laboratory Construction Project of Guangzhou Science and Technology Bureau(202102100007) （202102100007）

supported by the Clinical Frontier Technology Program of the First Affiliated Hospital of Jinan University,China(No.JNU1AF-CFTP-2022-a01221) （No.JNU1AF-CFTP-2022-a01221）

Natural Science Foundation of Guangdong Province(2021A1515012154,2019A1515011082,2017A030313665,2018A030313544,2020B1515120038) （2021A1515012154,2019A1515011082,2017A030313665,2018A030313544,2020B1515120038）

Science and Technology Projects in Guangzhou(201707010493,202102010069) （201707010493,202102010069）

Macao Foundation for Development of Science and Technology(0029/2019/A) （0029/2019/A）

Youth Talent Support Project of Guangzhou Association for Science&Technology(X20200301018) （X20200301018）

pilot project of clinical collaboration from National Administration of Traditional Chinese Medicine and National Health Commission of the People’s Republic of China and Logistics Support Department of the Central Military Commission。（）

Bone Research

OACSCDMEDLINE

ISSN：2095-4700

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