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癌症预康复在胰腺癌手术患者中的临床应用

于洁 杨莉 王彬 卢维娜 程艳爽

解放军医学院学报2023,Vol.44Issue(11):1235-1240,6.
解放军医学院学报2023,Vol.44Issue(11):1235-1240,6.DOI:10.12435/j.issn.2095-5227.2023.097

癌症预康复在胰腺癌手术患者中的临床应用

Clinical application of cancer prehabilitation program in pancreatic cancer patients undergoing surgery

于洁 1杨莉 2王彬 2卢维娜 1程艳爽2

作者信息

  • 1. 解放军医学院,北京 100853
  • 2. 解放军总医院第一医学中心肝胆胰外科医学部,北京 100853
  • 折叠

摘要

Abstract

Background Cancer prehabilitation is a preoperative intervention involving nutrition,exercise,and psychological measures from diagnosis to the beginning of treatment,which can improve postoperative outcomes.Objective To explore the application effect of cancer prehabilitation in pancreatic cancer patients undergoing surgery.Methods Patients undergoing pancreatic cancer surgery admitted to hospital from July 2022 to February 2023 were recruited as the study objects,among which patients admitted from July to October 2022 were included in the control group,and patients admitted from November 2022 to February 2023 were included in the prehabilitation group.The control group received routine preoperative intervention,and the prehabilitation group received cancer prehabilitation on the basis of the control group,including nutritional support,exercise intervention and psychological nursing.The 6-minute walking test(6MWT),Nutrition Risk Screening 2002(NRS2002),body mass index(BMI),the Hospital Anxiety and Depression Scale(HADS)at 1 day before surgery and early postoperative recovery indicators were compared between the two groups.Results A total of 47 patients were included,including 23 cases in the control group and 24 cases in the prehabilitation group.There was no significant difference in baseline general information such as age and gender between the two groups(P>0.05).In the prehabilitation group,the 6MWD([508.75±56.57]m vs[464.35±60.78]m),NRS2002(2.50±0.78 vs 3.13±1.22),BMI([24.53±1.43]kg/m2 vs[22.35±3.05]kg/m2),HADS-A(3.13±1.99 vs 5.35±1.85),HADS-D(2.96±2.49 vs 4.70±1.96)at 1 day before surgery were superior to control group,the differences were statistically significant(P<0.05).The off-bed time([38.29±2.46]h vs[40.39±2.76]h),the first time to exhaust([59.13±3.66]h vs[61.74±3.44]h),the time to defecate([71.00±4.74]h vs[74.87±3.70]h)were improved compared with the control group,and the differences were statistically significant(P<0.05).There was no significant difference in postoperative hospital stay between the two groups(P>0.05).None of the patients had any adverse events such as fall or cardiac and respiratory arrest.Conclusion Cancer prehabilitation is effective in improving motor function,nutritional status and psychological state of pancreatic cancer patients and promoting postoperative recovery.

关键词

胰腺癌/癌症预康复/加速康复/手术患者/外科护理

Key words

pancreatic cancer/cancer prehabilitation/accelerate recovery/surgical patients/surgical nursing

分类

医药卫生

引用本文复制引用

于洁,杨莉,王彬,卢维娜,程艳爽..癌症预康复在胰腺癌手术患者中的临床应用[J].解放军医学院学报,2023,44(11):1235-1240,6.

解放军医学院学报

OACSTPCD

2095-5227

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