解放军医学院学报2023，Vol.44Issue(12)：1330-1334,5.DOI:10.12435/j.issn.2095-5227.2023.132
高压氧预处理对加速度耐力不良飞行员心血管功能的影响
Effect of hyperbaric oxygen preconditioning on cardiovascular function in pilots with poor acceleration endurance
摘要
Abstract
Background It has been suggested that hyperbaric oxygen preconditioning(HBOP)can improve pilot acceleration endurance,and the mechanism may be related to improvement of autonomic function,but there are few researches on this.Objective To investigate the effect of HBOP on lower body negative pressure(LBNP)endurance in pilots with poor acceleration endurance,and detect autonomic function-related indexes such as cardiac quantum spectrum(CQS)and reactive hyperemia index(RHI),so as to explore the mechanisms by which HBOP improves acceleration endurance.Methods Pilots with poor acceleration tolerance at the Air Force Specialized Medical Center from February to July in 2021 were selected as subjects for a multi-person HBO chamber and a 3-times HBO exposure protocol.Oxygen inhalation was performed for a total of 95 min,once a day(fixed at 14:30-16:05 in the chamber),for 3 days.Using the subjects'own before-and-after control design method,their LBNP endurance,CQS and RHI were measured before and after HBOP.Results Twenty pilots were identified with poor acceleration tolerance.The cumulative stress index(CSI)was(-894.00±232.88)min·mmHg in subjects before HBOP and(-1 310.50±349.23)min·mmHg in subjects after HBOP(t=6.546,P<0.001),which suggested that the LBNP endurance increased significantly.The CQS index was(5.05±1.35)before HBOP and(4.30±1.26)after HBOP,which indicated a significant improvement in myocardial function indexes(t=2.680,P=0.015).The RHI values were(1.46±0.43)before HBOP and(1.78±0.54)after HBOP,indicating a significant improvement in vascular endothelial function indexes(t=-2.524,P=0.021).Conclusion HBOP can improve myocardial function and vascular endothelial function in pilots with poor acceleration tolerance,thereby improving their LBNP tolerance.关键词
高压氧/加速度耐力/飞行员/下体负压/心肌功能/血管内皮功能Key words
hyperbaric oxygen/accelerated endurance/flight personnel/lower body negative pressure/myocardial function/endothelial function分类
医药卫生引用本文复制引用
孙男男,黄杰,徐庆,朱姿英,晏沐阳,刘红巾..高压氧预处理对加速度耐力不良飞行员心血管功能的影响[J].解放军医学院学报,2023,44(12):1330-1334,5.基金项目
空军军医大学航空医学科技攻关项目(2021HKYX21) （2021HKYX21）
