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靶向药物制剂研究进展

安琪 李爽 杨德智 吕扬 杜冠华

医药导报2024,Vol.43Issue(3):397-402,6.
医药导报2024,Vol.43Issue(3):397-402,6.DOI:10.3870/j.issn.1004-0781.2024.03.012

靶向药物制剂研究进展

Research Advances in Targeted Drug Delivery System

安琪 1李爽 1杨德智 1吕扬 1杜冠华2

作者信息

  • 1. 北京协和医学院中国医学科学院药物研究所晶型药物研究北京市重点实验室,北京 100050
  • 2. 北京协和医学院中国医学科学院药物研究所药物靶点研究与新药筛选北京市重点实验室,北京 100050
  • 折叠

摘要

Abstract

In recent years,due to the development of disciplines such as molecular biology,cell biology,and materials science,the research of targeted therapy drugs has become a hot spot.Compared with conventional drugs,targeted therapy drugs can selectively increase the concentration and effectively reduce the toxic side effects of drugs in target tissues,which is an ideal way of drug delivery.Nanomaterial is receiving more attention for its superior performance in animals.The application and develop-ment of nanocrystals in targeted drug delivery systems has effectively broken the limitation of insoluble drugs and plays an indis-pensable role in drug delivery systems.In this paper,we briefly reviewed the characteristics and classification of targeted therapy drugs and the application of nanocrystals in pharmaceutical research to provide a reference for the related research.

关键词

靶向药物制剂/靶向药物/纳米晶体/难溶性药物

Key words

Target drug delivery system/Targeted therapy drug/Nanocrystals/Insoluble drug

分类

化学化工

引用本文复制引用

安琪,李爽,杨德智,吕扬,杜冠华..靶向药物制剂研究进展[J].医药导报,2024,43(3):397-402,6.

基金项目

国家自然科学基金面上项目(22278443) (22278443)

国家药品标准制修订研究课题(2022Y14) (2022Y14)

中国医学科学院医学与健康科技创新工程项目(2022-I2M-1-015). (2022-I2M-1-015)

医药导报

OA北大核心CSTPCD

1004-0781

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