针刺研究2024，Vol.49Issue(2)：171-176,6.DOI:10.13702/j.1000-0607.20221256
"补肾益髓"法艾灸治疗膝关节骨关节炎的疗效观察
Effect of moxibustion for"nourishing the kidney and benefiting the marrow"on knee osteoarthritis
摘要
Abstract
Objective To compare the clinical effect between two acupoint regimens of moxibustion on knee osteoarthritis(KOA),and observe the influences on the serum content of interleukin 1α(IL-1α),interleukin-17A(IL-17A),tumor necrosis factor α(TNF-α),bone gla protein(BGP)and osteoprotegerin(OPG).Methods KOA pa-tients were randomly divided into an observation group(40 cases,2 cases dropped off)and a control group(40 cases,3 cases dropped off).In the observation group,moxibustion was applied to Xiyan(EX-LE5),Dubi(ST35),Zusanli(ST36),Dazhu(BL11),Xuanzhong(GB39)and Yongquan(KI1)on the affected side.In the control group,EX-LE5,ST35 and ST36 were selected on the affected side.One session of treatment took 30 min in each group,delivered 3 times a week and the duration of treatment was 4 weeks.The scores of Western Ontario and McMaster University(WOMAC)and visual analogue scale(VAS)were observed and the serum content of IL-1α,IL-17A,TNF-α,BGP and OPG of the two groups were measured before and after treatment.Results Compared with those before treatment,the WOMAC score,VAS score and the serum content of IL-1α,IL-17A and TNF-α were decreased(P<0.05),and the content of BGP and OPG were increased(P<0.05)after treatment.Compared with the control group,the WOMAC score,VAS score and the serum content of IL-1α and TNF-α in the observation group were lower(P<0.05),and the content of BGP and OPG were higher(P<0.05).The total effective rate of the observation group was 89.5%(34/38),and that of the control group was 83.8%(31/37),with no statistically significant difference.Conclusion Moxibustion therapy of"nourishing the kidney and benefiting the marrow"can relieve joint pain,improve joint function,reduce the level of inflammatory factors and ameliorate bone metabolic indicators.The effect of the acupoint regimen in this moxi-bustion therapy is better than that of the local acupoint selection.关键词
艾灸/膝关节骨关节炎/骨代谢/炎性因子Key words
Moxibustion/Knee osteoarthritis/Bone metabolism/Inflammatory factors引用本文复制引用
王佩,王刘玉,谢舜名,王莉莉,王红恩,于建新,常永志,朱维杰.."补肾益髓"法艾灸治疗膝关节骨关节炎的疗效观察[J].针刺研究,2024,49(2):171-176,6.基金项目
江苏省卫生健康委医学科研项目(No.M2020039) （No.M2020039）
