中国全科医学2024，Vol.27Issue(12)：1424-1430,7.DOI:10.12114/j.issn.1007-9572.2023.0244
血脂异常与结直肠锯齿状病变、结直肠癌相关性研究进展
Research Progress on the Correlation of Dyslipidemia with Colorectal Serrated Lesions and Colorectal Cancer
摘要
Abstract
Dyslipidemia may be related to the occurrence and development of colorectal tumors.Numerous studies have confirmed that dyslipidemia increases the risk of colorectal adenomas at present;however,the association of dyslipidemia with colorectal serrated lesions and colorectal cancer is still controversial,and there are few relevant reviews in China.This article comprehensively explores the correlation of dyslipidemia with colorectal serrated lesions and colorectal cancer,analyzes the possible causes of controversy,identifies the directions of subsequent researches,and discusses the role of dyslipidemia in the occurrence and progression of colorectal tumors.This article indicates that dyslipidemia is associated with colorectal serrated lesions and colorectal cancer.Dyslipidemia may be involved in the development of colorectal tumors through the interaction of multiple mechanisms such as insulin resistance,inflammatory factors,oxidative stress,high-fat diet and immunosuppression.The incidence of colorectal cancer is increasing yearly with a relatively slower natural course and more definite precancerous lesions.Therefore,the clarification of correlation between lipid indexes and colorectal tumors can facilitate early prevention and targeted screening of colorectal tumors and provide a reference for formulating targeted prevention strategies for colorectal cancer.关键词
高脂血症/血脂异常/结直肠肿瘤/结直肠锯齿状病变/结直肠癌/综述Key words
Hyperlipidemias/Dyslipidemias/Colorectal neoplasms/Colorectal serrated lesions/Colorectal/cancer/Review分类
医药卫生引用本文复制引用
冉东升,逯艳艳,辛春玲,马颖才..血脂异常与结直肠锯齿状病变、结直肠癌相关性研究进展[J].中国全科医学,2024,27(12):1424-1430,7.基金项目
青海省卫生健康系统指导性计划课题(2022-wjzdx-11) （2022-wjzdx-11）
