自体牙骨移植材料修复牙槽骨缺损的应用效果研究OACSTPCD

Objective To investigate the clinical effect of autogenous tooth graft material combined with guided bone re-generation therapy(GBR)on alveolar bone defects.Methods A total of 82 patients requiring GBR to repair alveolar bone defect were selected,who received treatment from January 2020 to October 2021 in the Stomatology Department of the First Affiliated Hospital of Chongqing Medical University.According to the random number table method,patients were divided into experimental group(42 patients)and control group(40 patients).In the experimental group,autoge-nous tooth graft material was made during implantation and was implanted into the alveolar bone defect.In the control group,patients were implanted with Bio-Oss® bone meal in alveolar bone defect.The implantation success rate,corre-sponding bone tissue indexes,such as buccal lingual bone plate width and marginal bone absorption volume,implant sta-bility quotient(ISQ),and incidence of adverse reactions were compared between the two groups.Results There was no significant difference in the success rate of implantation between the experimental group and the control group at 1 year after surgery(x2=0.186,P=0.735).There was no significant difference in the width of the buccal lingual bone plate between the two groups before or immediately after surgery(P＞0.05).The width of the buccal lingual bone plate in the experimental group was higher than that in the control group at 12 months after surgery,and the differ-ence was statistically significant(t=3.872,P=0.005).The marginal bone resorption volume of the experimental group was lower than that of the control group at 12 months after operation,and the difference was statistically significant(t=-3.030,P=0.039).ISQ of the experimental group was significantly higher than that of the control group at 6 months after surgery(t=2.996,P=0.017).There was no significant difference in the incidence of adverse reactions be-tween the two groups(x2=0.076,P=0.532).Conclusion Autogenous tooth graft material and Bio-Oss® bone meal for alveolar bone defects both have high success rate.Compared with Bio-Oss® bone meal,autogenous tooth graft material can effectively improve the width of alveolar bone after surgery and delay the bone absorption at the edge of the implant,resulting in better implant stability.With high biosafety,autogenous tooth graft material is worthy of further promotion in clinical practice.