植物学报2023，Vol.58Issue(6)：935-945,11.DOI:10.11983/CBB23050
适配体技术及其在植物科学研究中的应用
Aptamers and Their Applications in Plant Science Researches
摘要
Abstract
Aptamers are single-stranded oligonucleotides or short peptides that are screened and selected from artificially synthesized libraries and can specifically bind to the target molecules.Aptamers can bind and regulate the activities of its target molecules based on their own structure and sequence,and are applied to in vivo molecular function researches and new drug preparation explorations.In recent years,peptide aptamers have been widely used in various fields,such as medicine,genetics and molecular biology,which is becoming a highly efficient,spe-cific and powerful new tool.In plants,with the establishment,application and promotion of the corresponding sys-tem,aptamers have gradually been become an effective tool for studying plant molecular functions.In this review,we summarized the classification,screening principles and basic applications of aptamers,with special emphasis on their applications in plant breeding.It can be expected that with the development of molecular design bio-breeding technology,aptamers can be cooperated with transgenic techniques and become a valuable application tool in the plant science fields.关键词
适配体/核酸/多肽/植物/筛选Key words
aptamer/nucleic acid/peptide/plants/screening引用本文复制引用
李奕,张曦,袁艳辉,公丕昌,林金星..适配体技术及其在植物科学研究中的应用[J].植物学报,2023,58(6):935-945,11.基金项目
中央高校基本科研业务费专项资金(No.BLX202116)、中国科学院青年创新促进会(No.2019081)、国家自然科学基金(No.32030010,No.32000558)、北京市自然科学基金(No.5232016)和抗松材线虫病高产油松新品种设计与培育(No.2022ZD0401605) （No.BLX202116）
