海南医学院学报2024，Vol.30Issue(4)：304-308,5.DOI:10.13210/j.cnki.jhmu.20230609.001
非小细胞肺癌ctDNA监测耐药相关伴随基因研究进展
Research progress on dynamic monitoring of ctDNA and drug resistance related concomitant mutations in non-small cell lung cancer
摘要
Abstract
Owing to significantly prolonged survival,targeted therapy has become standardized recommendation for ad-vanced non-small cell lung cancer patients with mutated driver genes.However,the genetic status of lung cancer patients is dynam-ic.By dynamically monitoring the evolution of genes status,differential genes and concomitant genes related to progressive disease could be confirmed early,so as to achieve a more accurate and comprehensive insight of the whole process management of targeted therapy for lung cancer patients.Under the guidance of accurate genetic testing results,it is helpful to provide patients with more effective,long-term,and stable individualized targeted therapy.关键词
非小细胞肺癌/ctDNA/靶向治疗/伴随突变/研究进展Key words
Non-small cell lung cancer/CtDNA/Targeted therapy/Concomitant mutations/Research progress分类
医药卫生引用本文复制引用
薛崇祥,张旭,鲁星妤,崔慧娟..非小细胞肺癌ctDNA监测耐药相关伴随基因研究进展[J].海南医学院学报,2024,30(4):304-308,5.基金项目
National Natural Science Foundation of China(81873396) （81873396）
Capital Health Development Research Project(2018-2-4065) （2018-2-4065）
Project of China-Japan Friendship Hospital(2018-HX-26)国家自然科学基金(81873396) （2018-HX-26）
首都卫生发展科研专项(2018-2-4065) （2018-2-4065）
中日友好医院课题(2018-HX-26) （2018-HX-26）
