中国实用神经疾病杂志2024，Vol.27Issue(3)：351-355,5.DOI:10.12083/SYSJ.230818
益生菌肠内营养支持联合经颅磁刺激在脑卒中后吞咽障碍康复中的应用
Application of probiotic enteral nutrition support combined with transcranial magnetic stimulation in the rehabilitation of dysphagia after stroke
摘要
Abstract
Objective To investigate clinical application of probiotic enteral nutrition support combined with transcranial magnetic stimulation in the rehabilitation of swallowing disorders after stroke.Methods Ninety-eight stroke patients admitted to the Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine from January 2019 to December 2021 were selected as the subjects.They were randomly divided into the observation group and the control group by computer,with 49 cases in each group.The control group was treated by regular nutritional support and transcranial magnetic stimulation,observation group applied probiotic enteral nutrition support treatment on the basis of the control group.The clinical efficacy,swallowing function score,nutritional indicators,immune function,intestinal barrier function,and quality of life scores between two groups were compared.Results The clinical efficacy of the observation group after treatment was better than control group(P<0.05).After treatment,the scores of kubote water swallowing test(KWST),functional dysphagia scale(FDS)and eating assessment questionnaire-10(EAT-10)in the observation group were lower that those of the control group(P<0.05).The levels of serum albumin(ALB),hemoglobin(Hb),and prealbumin(PAB)in the observation group were higher than those of the coutrol group(P<0.05).The levels of immunoglobulin A(IgA),immunoglobulin G(IgG),and immunoglobulin M(IgM)in the observation group were higher those of the control group(P<0.05).The intestinal mucosal barrier function indicators including diamine oxidase(DAO),D-lactate(D-LA)and ET levels were lower than those of the control group(P<0.05).Conclusion The combination of probiotic enteral nutrition support and transcranial magnetic stimulation has a good effect in the rehabilitation treatment of swallowing disorders after stroke.It can improve the patient's swallowing function score and nutritional health status,and it can enhance their immune function and intestinal mucosal barrier function.关键词
脑卒中/吞咽障碍/经颅磁刺激/益生菌/肠内营养/免疫功能/肠黏膜屏障功能Key words
Stroke/Swallowing disorders/Transcranial magnetic stimulation/Probiotics/Enteral nutrition/Immune function/Intestinal mucosal barrier function分类
医药卫生引用本文复制引用
张玉珍,于小明,徐海辰,马双双..益生菌肠内营养支持联合经颅磁刺激在脑卒中后吞咽障碍康复中的应用[J].中国实用神经疾病杂志,2024,27(3):351-355,5.基金项目
上海中医药大学附属第七人民医院人才培养计划(编号:QMX2021-10 （）
PWZzb2022-11) （）
