解剖学杂志2023，Vol.46Issue(6)：530-533,4.DOI:10.3969/j.issn.1001-1633.2023.06.012
铁死亡在心血管疾病中的作用及研究进展
The role and research progress of ferroptosis in cardiovascular diseases
李鹏达 1王峰 1郭志坤 1常玉巧1
作者信息
- 1. 新乡医学院河南省医用组织再生重点实验室,新乡 453003
- 折叠
摘要
Abstract
Ferroptosis is a newly discovered form of regulated cell death in recent years.It is characterized by iron overload,lipid peroxidation,and reactive oxygen species accumulation.Ferroptosis is regulated by various metabolic pathways such as iron metabolism,lipid metabolism,and amino acid metabolism.Ferroptosis plays an important regulatory role in cardiovascular diseases such as acute myocardial infarction,myocardial ischemia-reperfusion injury,heart failure,and atherosclerosis,which is closely related to myocardial cell injury.In this review,we discussed the role of ferroptosis in cardiovascular diseases to explore new targets for the treatment of cardiovascular diseases.关键词
铁死亡/铁代谢/心肌细胞/心血管疾病Key words
ferroptosis/iron metabolism/cardiomyocytes/cardiovascular diseases引用本文复制引用
李鹏达,王峰,郭志坤,常玉巧..铁死亡在心血管疾病中的作用及研究进展[J].解剖学杂志,2023,46(6):530-533,4.
