肿瘤预防与治疗2024，Vol.37Issue(2)：95-100,6.DOI:10.3969/j.issn.1674-0904.2024.02.001
微束放疗的进展与挑战
Advances and Challenges in Microbeam Radiotherapy
摘要
Abstract
Microbeam irradiation is an irradiation technology that gives a narrow micron beam in a spatially spaced way.Mi-crobeam irradiation with therapeutic purpose is called microbeam radiotherapy(MRT).Extremely high X-ray dose is released at a very high dose rate within a very narrow time window.At present,a large number of preclinical studies have reported that it has sig-nificant therapeutic potential and normal tissue protection effect.In particular,preclinical studies of brain tumors have shown ex-traordinary protection effects of normal brain tissue.In addition,Spatially fractionated radiation therapy,which is conceptually similar to MRT,has achieved some results in clinical practice.This study reviews the current development of MRT from basic to clinical and elaborates the advances and challengas in research on this field.关键词
放疗/微束放疗/质子微束/生物效应Key words
Radiotherapy/Microbeam radiation therapy/Proton microbeam/Biological effect分类
医药卫生引用本文复制引用
徐鹏,郎锦义..微束放疗的进展与挑战[J].肿瘤预防与治疗,2024,37(2):95-100,6.基金项目
This study was supported by grants from Science and Technology Department of Sichuan Province(No.2020YFH0168). 四川省科技厅国际科技创新合作重点课题(编号:2020YFH0168) （No.2020YFH0168）
