实用休克杂志（中英文）2023，Vol.7Issue(6)：333-336,350,5.
入院肌酐清除率对急性非ST段抬高型心肌梗死合并NT-proBNP水平升高患者预后的预测价值
Predictive value of admission creatinine clearance in patients with acute non-ST segment elevation myocar-dial infarction and elevated NT-proBNP levels
摘要
Abstract
Objective To investigated the effect of admission creatinine clearance rate on the outcome of acute non-ST segment elevation myocardial infarction(NSTEMI)patients with elevated NT-proBNP levels.Methods 233 patients with NSTEMI and elevated NT-proBNP levels were ad-mitted in 14 medical centers in China between October 2017 and October 2021.According to the level of admission creatinine clearance rate,all the patients were divided into low Ccr group(n=131)and normal Ccr group(n=102).The primary outcome was major adverse cardiovascular events(MACE)during hospitalization and at 180 days after hospitalization.Results Compared to the normal Ccr group,MACE was higher during hospitalization but no significant differences[6.9％(7/102)vs.5.3％(7/131);x2=0.23,P=0.63],however,MACE is significant higher at 180 days[19.6％(20/102)vs.9.9％(13/131);x2=4.42,P=0.04].Compared to the normal Ccr group,180 days survival rate was lower in the low Ccr group(logrank test,P=0.017).Conclusions Ccr＜80mL/min at admission was an independent predictor of 180-days MACE in NSTEMI pa-tients with elevated NT-proBNP levels.关键词
急性非ST段抬高型心肌梗死/肌酐清除率/不良心血管事件Key words
Acute non-ST segment elevation myocardial infarction/Creatinine clearance rate/Major adverse cardiovascular events引用本文复制引用
于丹玉,高璐瑶,程凯,薛丽,边圆..入院肌酐清除率对急性非ST段抬高型心肌梗死合并NT-proBNP水平升高患者预后的预测价值[J].实用休克杂志（中英文）,2023,7(6):333-336,350,5.基金项目
国家科技基础资源调查专项(项目编号:2018FY100600) （项目编号:2018FY100600）
国家重点研发计划(项目编号:2020YFC1512700、2020YFC1512705、2020YFC1512703) （项目编号:2020YFC1512700、2020YFC1512705、2020YFC1512703）
山东省重点研发计划(项目编号:2021ZLGX02) （项目编号:2021ZLGX02）
