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不同DIC评分系统对脓毒症患者凝血功能障碍早期诊断和预后预测的价值

耿方敏 贺元旦 李文娟 刘茜茜 张红微 陆章平 魏莲花

实用医学杂志2024,Vol.40Issue(2):248-252,5.
实用医学杂志2024,Vol.40Issue(2):248-252,5.DOI:10.3969/j.issn.1006-5725.2024.02.021

不同DIC评分系统对脓毒症患者凝血功能障碍早期诊断和预后预测的价值

Values of different DIC scoring systems in early diagnosis and prognosis prediction of coagulation dysfunc-tion in sepsis patients

耿方敏 1贺元旦 1李文娟 1刘茜茜 1张红微 2陆章平 3魏莲花4

作者信息

  • 1. 甘肃中医药大学(兰州 730000)
  • 2. 兰州大学(兰州 730000)
  • 3. 宁夏医科大学(银川 750004)
  • 4. 甘肃省人民医院检验科(兰州 730000)
  • 折叠

摘要

Abstract

Objective To evaluate five types of DIC scoring systems based on sepsis patients,to explore the values of different DIC scoring systems in the occurrence and prognosis of DIC in sepsis patients,and to compare the applicability of different DIC scoring systems for sepsis complicated with DIC.Methods Laboratory indexes and clinical data from sepsis patients who had been hospitalized in Gansu Provincial People's Hospital from December 1,2019 to December 31,2021 were retrospectively analyzed within 24 hours.Five types of DIC scoring systems were used to score,and the difference of diagnostic rate and discharge outcome in sepsis patients with different severity was compared.The ROC curves of five DIC scoring systems were established to evaluate the accu-racy of DIC in sepsis patients.Results The fatality rate of sepsis increased with the severity of sepsis(P<0.05).There were statistically significant differences in discharge outcomes between DIC and non-DIC in the five scoring systems(P<0.05).JMHW,CDSS and part of ISTH were detected in JAAM cases,while ISTH was detected in non-dominant ISTH cases.ISTH,JAAM,JMHW,CDSS,and non-dominant ISTH5 scoring systems were used to diagnose DIC,and absence of full health restoration and death were 3.0,3.8,4.2,3.9,and 3.0 times higher than non-DIC cases,respectively.Conclusion JAAM scoring system has higher diagnostic rate and sensitivity for adult sepsis.CDSS and JMHW scoring systems are more accurate in predicting the prognosis of sepsis patients.

关键词

脓毒症/DIC/评分系统/诊断效能

Key words

sepsis/DIC/scoring systems/diagnostic efficacy

分类

医药卫生

引用本文复制引用

耿方敏,贺元旦,李文娟,刘茜茜,张红微,陆章平,魏莲花..不同DIC评分系统对脓毒症患者凝血功能障碍早期诊断和预后预测的价值[J].实用医学杂志,2024,40(2):248-252,5.

基金项目

国家自然科学基金资助项目(编号:81960385) (编号:81960385)

甘肃省人民医院院内科研基金项目(编号:16GSSY2-6) (编号:16GSSY2-6)

兰州市中医药管理局科研项目(编号:GZK-2012-17) (编号:GZK-2012-17)

实用医学杂志

OA北大核心CSTPCD

1006-5725

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