实用医学杂志2024，Vol.40Issue(4)：460-465,6.DOI:10.3969/j.issn.1006-5725.2024.04.004
癫痫患者共患抑郁和焦虑危险因素分析及其与生存质量的关系
Risk factors of depression and anxiety in epilepsy patients and their relationship with quality of life
摘要
Abstract
Objective To explore the risk factors of depression and anxiety in adult patients with epilepsy and their relationship with quality of life.Methods From May 2022 to January 2023,patients diagnosed with epilepsy(aged≥18 years)in the department of neurology of our hospital were collected.General demographic data and disease-related information were recorded.Quality of life,depression and anxiety scales were measured in all patients.SPSS26.0 software was used for multiple linear regression analysis,multiple ordered Logistic regression analysis,rank sum test,Pearson correlation analysis,etc.Results Among the 111 patients,49.5%had depression and 43.2%had anxiety.Depression score and anxiety score were correlated with attack type,attack frequency,quality of life and right temporal lobe,and there was a significant negative correlation between life quality score and anxiety and depression score(P<0.01).Seizure frequency,seizure type and right temporal lobe were common risk factors for depression and anxiety in patients with epilepsy(P<0.05).Conclusion Epileptic depression and anxiety were affected by seizure frequency and seizure type,and this bad mood further affected the quality of life of patients.No clear link has been found between the lateralization of seizures and the presence of depression and anxiety states,and further research is needed.关键词
共患病/神经网络/下丘脑-垂体-肾上腺轴/偏侧性/癫痫/抑郁/焦虑Key words
comorbidity/neural network/hypothalamic-pituitary-adrenal axis/laterality/epilepsy/depression/anxiety分类
医药卫生引用本文复制引用
韩文杰,周友田,黎振声,康健捷,邓兵梅..癫痫患者共患抑郁和焦虑危险因素分析及其与生存质量的关系[J].实用医学杂志,2024,40(4):460-465,6.基金项目
广东省医学科学技术研究基金项目(编号:A2022402) （编号:A2022402）
