实用肝脏病杂志2024，Vol.27Issue(2)：246-250,5.DOI:10.3969/j.issn.1672-5069.2024.02.022
一组非肝硬化性门静脉高压症病因分析和诊断路径探讨
Etiology and diagnostic roadmap in patients with non-cirrhotic portal hypertension
摘要
Abstract
Objective The aim of this study was to investigate the etiology and diagnostic roadmap in patients with non-cirrhotic portal hypertension(NCPH).Methods 105 patients with NCPH were encountered in the First Affiliated Hospital,Guangxi Medical University between September 2020 and March 2022,and the etiologies and the main diagnostic methods were summarized retrospectively.Results The etiologies of NCPH in our series included prehepatic,hepatic and posthepatic entities;the common diseases were found with prehepatic portal hypertension(PH)in 69 cases(65.7%),the hepatic PH in 21 cases(20.0%)and the posthepatic PH in 4 cases(3.8%);the common diseases in patients with prehepatic ph were pancreaticogenic diseases in22 cases(31.9%),portal vein obstruction in15 cases(21.7%),and hematologic diseases in 15 cases(21.7%);the main diagnostic methods were imaging examination in 28 cases(40.6%),gastrointestinal endoscopy in 14 cases(20.3%)and bone marrow biopsies in12 cases(17.4%);the top three methods for the etiological diagnosis in patients with NCPH were imaging examination(33.3%),comprehensive analysis(18.1%)and gastrointestinal endoscopy(13.9%).Conclusion The prehepatic PH should be considered firstly in patients with NCPH presentation,the laboratory and imaging examinations should be performed routinely,and the gastrointestinal endoscopy and bone marrow biopsy might be performed if necessary.For those without clear diagnosis after routine examination,the hepatic and posthepatic PH must be considered,and liver biopsy and inferior vena cava puncture angiography should be done for further validation of diagnosis.关键词
非肝硬化性门静脉高压/病因/诊断路径Key words
Non-cirrhotic portal hypertension/Etiology/Diagnostic roadmap引用本文复制引用
冯彦菲,苏明华,殷倩冰,黎清梅,苏土梅,梁蘅恺,韦璐,黄建芳,江建宁..一组非肝硬化性门静脉高压症病因分析和诊断路径探讨[J].实用肝脏病杂志,2024,27(2):246-250,5.基金项目
国家自然科学基金资助项目(编号:81960115,82260124) （编号:81960115,82260124）
广西壮族自治区病毒性肝炎防治研究重点实验室开放课题基金项目(编号:GXCDCKL202001) （编号:GXCDCKL202001）
教育部区域性高发肿瘤早期防治研究重点实验室自主课题(编号:GKE-ZZ202107) （编号:GKE-ZZ202107）
