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二甲双胍联合门冬胰岛素治疗妊娠糖尿病的临床效果

冯晓蕾 刘安平 张慧媛

妇儿健康导刊2024,Vol.3Issue(2):108-111,4.
妇儿健康导刊2024,Vol.3Issue(2):108-111,4.

二甲双胍联合门冬胰岛素治疗妊娠糖尿病的临床效果

Clinical effect of Metformin combined with Insulin Aspart in the treatment of gestational diabetes mellitus

冯晓蕾 1刘安平 2张慧媛3

作者信息

  • 1. 青岛市市北区同安路街道社区卫生服务中心全科,山东青岛 266000
  • 2. 青岛市市北区同安路街道社区卫生服务中心公卫科,山东青岛 266000
  • 3. 青岛市市北区同安路街道社区卫生服务中心妇女保健科,山东青岛 266000
  • 折叠

摘要

Abstract

Objective To explore the clinical effect of Metformin combined with Insulin Aspart in the treatment of gestational diabetes mellitus.Methods A total of 70 patients with gestational diabetes mellitus from January 2018 to January 2023 in Tong'an Road Street Community Health Service Center of Shibei District in Qingdao City were selected as the study objects.All the patients were divided into the control group and the observation group by the random number table method,with 35 cases in each group.The control group was treated with Insulin Aspart,and the observation group was treated with Metformin on the basis of the control group.The maternal and neonatal adverse situation,symptom scores and blood glucose levels were compared between the two groups.Results After treatment,the total incidence of adverse situation of newborns in the observation group was lower than that in the control group(P<0.05).The incidence rate of polyhydramnios,premature rupture of membranes and postpartum hemorrhage and cesarean section rate in the observation group were lower than those in the control group(P<0.05).The scores of polyphagia,thirst and fond of drinking,limb numbness,fatigue and lack of strength and excessive urination in the observation group were lower than those in the control group(P<0.05).The levels of fasting plasma glucose and 2 hour postprandial blood glucose in the observation group were lower than those in the control group(P<0.05).Conclusion Metformin combined with Insulin Aspart has significant effect on gestational diabetes mellitus.

关键词

二甲双胍/门冬胰岛素/妊娠糖尿病

Key words

Metformin/Insulin Aspart/Gestational diabetes mellitus

分类

医药卫生

引用本文复制引用

冯晓蕾,刘安平,张慧媛..二甲双胍联合门冬胰岛素治疗妊娠糖尿病的临床效果[J].妇儿健康导刊,2024,3(2):108-111,4.

妇儿健康导刊

2097-115X

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