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Protective effects of dioscin against Parkinson's disease via regulating bile acid metabolism through remodeling gut microbiome/GLP-1 signaling

Zhang Mao Haochen Hui Xuerong Zhao Lina Xu Yan Qi Lianhong Yin Liping Qu Lan Han Jinyong Peng

药物分析学报(英文)2023,Vol.13Issue(10):1153-1167,15.
药物分析学报(英文)2023,Vol.13Issue(10):1153-1167,15.DOI:10.1016/j.jpha.2023.06.007

Protective effects of dioscin against Parkinson's disease via regulating bile acid metabolism through remodeling gut microbiome/GLP-1 signaling

Protective effects of dioscin against Parkinson's disease via regulating bile acid metabolism through remodeling gut microbiome/GLP-1 signaling

Zhang Mao 1Haochen Hui 1Xuerong Zhao 1Lina Xu 1Yan Qi 1Lianhong Yin 1Liping Qu 2Lan Han 3Jinyong Peng4

作者信息

  • 1. Department of Pharmaceutical Analysis,College of Pharmacy,Dalian Medical University,Dalian,Shenyang,116044,China
  • 2. Innovation Materials Research and Development Center,Botanee Research Institute,Yunnan Botanee Bio-technology Group Co.,Ltd.,Kunming,650106,China
  • 3. Department of Traditional Chinese Medicine Pharmacology,School of Pharmacy,Anhui University of Chinese Medicine,Hefei,230012,China
  • 4. Department of Pharmaceutical Analysis,College of Pharmacy,Dalian Medical University,Dalian,Shenyang,116044,China||Department of Pharmacology,School of Pharmacy,Weifang Medical University,Weifang,Shandong,261053,China
  • 折叠

摘要

关键词

Parkinson's disease/Dioscin/Gut microbiota/Bile acid metabolism/GLP-1

Key words

Parkinson's disease/Dioscin/Gut microbiota/Bile acid metabolism/GLP-1

引用本文复制引用

Zhang Mao,Haochen Hui,Xuerong Zhao,Lina Xu,Yan Qi,Lianhong Yin,Liping Qu,Lan Han,Jinyong Peng..Protective effects of dioscin against Parkinson's disease via regulating bile acid metabolism through remodeling gut microbiome/GLP-1 signaling[J].药物分析学报(英文),2023,13(10):1153-1167,15.

基金项目

The authors gratefully acknowledge funding from the Spring City Plan:The High-Level Talent Promotion and Training Project of Kunming and the Independent Research Fund of Yunnan Charac-teristic Plant Extraction Laboratory(Grant No.:2022YKZY001). (Grant No.:2022YKZY001)

药物分析学报(英文)

OACSCD

2095-1779

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