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首页|期刊导航|药物分析学报(英文)|Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission

Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission

Xiao-Ling Liang Lan Ouyang Nan-Nan Yu Zheng-Hua Sun Zi-Kang Gui Yu-Long Niu Qing-Yu He Jing Zhang Yang Wang

药物分析学报(英文)2023,Vol.13Issue(10):1168-1182,15.
药物分析学报(英文)2023,Vol.13Issue(10):1168-1182,15.DOI:10.1016/j.jpha.2023.06.005

Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission

Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission

Xiao-Ling Liang 1Lan Ouyang 1Nan-Nan Yu 1Zheng-Hua Sun 1Zi-Kang Gui 1Yu-Long Niu 1Qing-Yu He 2Jing Zhang 3Yang Wang1

作者信息

  • 1. MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes,Institute of Life and Health Engineering,College of Life Science and Technology,Jinan University,Guangzhou,510632,China
  • 2. MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes,Institute of Life and Health Engineering,College of Life Science and Technology,Jinan University,Guangzhou,510632,China||Department of Radiology,The First Affiliated Hospital of Jinan University and MOE Key Laboratory of Tumor Molecular Biology,Jinan University,Guangzhou,510632,China
  • 3. Department of Radiology,The First Affiliated Hospital of Jinan University and MOE Key Laboratory of Tumor Molecular Biology,Jinan University,Guangzhou,510632,China
  • 折叠

摘要

关键词

HDAC inhibitor/Pracinostat/CDK5/Mitochondrial fission/Acetylation/Drp1

Key words

HDAC inhibitor/Pracinostat/CDK5/Mitochondrial fission/Acetylation/Drp1

引用本文复制引用

Xiao-Ling Liang,Lan Ouyang,Nan-Nan Yu,Zheng-Hua Sun,Zi-Kang Gui,Yu-Long Niu,Qing-Yu He,Jing Zhang,Yang Wang..Histone deacetylase inhibitor pracinostat suppresses colorectal cancer by inducing CDK5-Drp1 signaling-mediated peripheral mitofission[J].药物分析学报(英文),2023,13(10):1168-1182,15.

基金项目

This work was supported by the National Natural Science Foundation of China(Grant Nos.:82103208,and 82002948),the Guangdong Basic and Applied Basic Research Foundation(Grant Nos.:2022A1515220212,and 2023A1515030115),National Key R& D Program of China(Grant No.:2020YFE0202200)and Jinan University National College Students'Innovation and Entrepre-neurship Training Program(Program No.:202110559085). (Grant Nos.:82103208,and 82002948)

药物分析学报(英文)

OACSCD

2095-1779

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