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诺欣妥联合芪苈强心胶囊治疗慢性心衰合并阵发性房颤的临床研究OA

Clinical Study of Entresto Combined with Qili Qiangxin Capsule in the Treatment of Chronic Heart Failure Complicated with Paroxysmal Atrial Fibrillation

中文摘要英文摘要

目的 探讨诺欣妥联合芪苈强心胶囊治疗心力衰竭(CHF)合并阵发性房颤(PAF)患者的临床效果.方法 94 例CHF合并PAF患者随机分为两组,对照组采用诺欣妥治疗,观察组采用诺欣妥联合芪苈强心胶囊治疗,比较两组的治疗效果、心功能指标、炎性指标.结果 观察组的治疗总有效率为 93.62%,显著高于对照组的 78.72%(P<0.05).治疗后,观察组的LVEF、PER均显著高于对照组,IL-6、TNF-α水平均显著低于对照组(P<0.05).结论 诺欣妥联合芪苈强心胶囊治疗CHF合并PAF患者的临床效果显著,能明显促进患者心功能恢复,减轻患者炎性反应.

Objective To explore the clinical effect of Entresto combined with Qili Qiangxin Capsule in the treatment of patients with chronic heart failure(CHF)complicated with paroxysmal atrial fibrillation(PAF).Methods 94 patients with CHF complicated with PAF were randomly divided into two groups.The control group was treated with Entresto,and the observation group was treated with Entresto combined with Qili Qiangxin Capsule.The therapeutic effect,cardiac function indicators and inflammatory indicators were compared between the two groups.Results The total effective rate of treatment in the observation group was 93.62%,significantly higher than 78.72%in the control group(P<0.05).After treatment,the LVEF and PER in the observation group were significantly higher than those in the control group,and the levels of IL-6 and TNF-α were significantly lower than those in the control group(P<0.05).Conclusions Entresto combined with Qili Qiangxin Capsule in the treatment of patients with CHF complicated with PAF has significant clinical effect,which can obviously promote the recovery of cardiac function and reduce the inflammatory response of patients.

韩贝;胡法国

郑州市第七人民医院心内科,河南郑州 450016

中医学

诺欣妥芪苈强心胶囊慢性心力衰竭阵发性房颤临床效果

EntrestoQili Qiangxin CapsuleChronic heart failureParoxysmal atrial fibrillationClinical effect

《临床医学工程》 2024 (002)

155-156 / 2

河南省医学科技攻关计划联合共建项目(LHGJ20220832)

10.3969/j.issn.1674-4659.2024.02.0155

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