临床医学工程2024，Vol.31Issue(2)：157-158,2.DOI:10.3969/j.issn.1674-4659.2024.02.0157
血清VEGF、TAP、CA125及HE4检测在卵巢上皮性癌诊断中的临床价值
Clinical Value of Serum VEGF,TAP,CA125 and HE4 Detection in the Diagnosis of Epithelial Ovarian Cancer
王亚茹 1张冬丽 1王宁1
作者信息
- 1. 河南大学淮河医院妇产科,河南开封 475000
- 折叠
摘要
Abstract
Objective To explore the value of serum VEGF,TAP,CA125 and HE4 detection in the diagnosis of epithelial ovarian cancer(EOC).Methods 191 patients with ovarian tumor surgery were divided into the observation group(EOC)and the control group(benign ovarian tumor)according to the pathological results.The levels of VEGF,TAP,CA125 and HE4 were compared between the two groups.The levels of each index in the early and advanced patients in the observation group were compared,and the efficiencies of each index in the diagnosis of EOC were analyzed.Results The levels of VEGF,TAP,CA125 and HE4 in the observation group were higher than those in the control group(P<0.001).In the observation group,the levels of VEGF,CA125 and HE4 in the advanced patients were higher than those in the early patients(P<0.05).The AUC and efficacy of combined detection of the four indicators in the diagnosis of EOC were better than those of single detection(P<0.05).Conclusions The expressions of VEGF,TAP,CA125 and HE4 in EOC patients are abnormally high,and combined detection can improve the diagnostic accuracy.关键词
VEGF/TAP/CA125/HE4/上皮性卵巢癌/诊断Key words
VEGF/TAP/CA125/HE4/Epithelial ovarian cancer/Diagnosis分类
医药卫生引用本文复制引用
王亚茹,张冬丽,王宁..血清VEGF、TAP、CA125及HE4检测在卵巢上皮性癌诊断中的临床价值[J].临床医学工程,2024,31(2):157-158,2.
