临床医学工程2024，Vol.31Issue(2)：209-210,2.DOI:10.3969/j.issn.1674-4659.2024.02.0209
奥美坎替美酯联合比索洛尔治疗射血分数降低型心衰患者的效果
Effect of Omecamtiv Mecarbil Combined with Bisoprolol in the Treatment of Patients with Heart Failure with Reduced E-jection Fraction
吴晓倩 1陆立志 1许云龙1
作者信息
- 1. 周口市太康县人民医院心血管内科,河南周口 461400
- 折叠
摘要
Abstract
Objective To explore the clinical effect of omecamtiv mecarbil combined with bisoprolol in the treatment of patients with heart failure with reduced ejection fraction.Methods A total of 435 patients with heart failure with reduced ejection fraction admitted to our hospital from January 2021 to January 2023 were selected and randomly divided into two groups.The control group was treated with bisoprolol,and the observation group was treated with omecamtiv mecarbil on the basis of the control group.The therapeutic effect,cardiac function,and levels of BNP and CRP were compared between the two groups.Results The total effective rate in the observation group was 89.45%,higher than 63.13%in the control group(P<0.05).After treatment,the levels of BNP and CRP in the observation group were lower than those in the control group(P<0.05).After treatment,LVEF and LVEDV in the observation group were higher than those in the control group,and LVESV and LVEDD were lower than those in the control group(P<0.05).Conclusions Omecamtiv mecarbil combined with bisoprolol is effective in the treatment of heart failure with reduced ejection fraction,and can improve the cardiac function of patients.关键词
奥美坎替美酯/比索洛尔/射血分数降低型心衰/心功能Key words
Omecamtiv mecarbil/Bisoprolol/Heart failure with reduced ejection fraction/Cardiac function分类
医药卫生引用本文复制引用
吴晓倩,陆立志,许云龙..奥美坎替美酯联合比索洛尔治疗射血分数降低型心衰患者的效果[J].临床医学工程,2024,31(2):209-210,2.
