医学新知2024，Vol.34Issue(2)：206-216,11.DOI:10.12173/j.issn.1004-5511.202312069
良性前列腺增生多组学生物标志物的研究进展
The research progress on multi-omics analysis biomarkers of benign prostatic hyperplasia
摘要
Abstract
Benign prostatic hyperplasia(BPH)is one of the most common benign diseases among the ageing male population with increasing prevalence,which can cause lower urinary tract symptoms and seriously affect the quality of life of patients.However,currently commonly used diagnostic methods(IPSS,rectal finger imaging,etc.)are difficult to detect to differentiate benign/malignant BPH,so biomarkers are relatively ideal for screening BPH and developing relevant targeted therapeutic drugs.This article reviews the research progress of multi-omics analysis related biomarkers in benign prostatic hyperplasia,including genetic,protein,metabolic,and microbial biological biomarkers,intending to provide direction and basis for early diagnosis of benign prostatic hyperplasia.关键词
良性前列腺增生/生物标志物/多组学测序/衰老Key words
Benign prostatic hyperplasia/Biomarkers/Multi-omics analysis/Aging引用本文复制引用
钱信行,顾佳敏,陆沛文,杨室淞,方程,李晓东,曾宪涛..良性前列腺增生多组学生物标志物的研究进展[J].医学新知,2024,34(2):206-216,11.基金项目
国家自然科学基金青年科学基金项目(82200862) （82200862）
湖北省卫生健康委面上项目(WJ2023M058) （WJ2023M058）
