首页|期刊导航|药物分析学报(英文)|Gut microbiota-based pharmacokinetic-pharmacodynamic study and molecular mechanism of specnuezhenide in the treatment of colorectal cancer targeting carboxylesterase
Gut microbiota-based pharmacokinetic-pharmacodynamic study and molecular mechanism of specnuezhenide in the treatment of colorectal cancer targeting carboxylesterase
Hang Yu Zhao Zhai Jingyue Wang Jiandong Jiang Yan Wang Hui Xu Xinyu Yang Zhengwei Zhang Jiachun Hu Jinyue Lu Jie Fu Mengmeng Bu Haojian Zhang
药物分析学报(英文)2023,Vol.13Issue(9):1024-1040,17.
药物分析学报(英文)2023,Vol.13Issue(9):1024-1040,17.DOI:10.1016/j.jpha.2023.06.012
Gut microbiota-based pharmacokinetic-pharmacodynamic study and molecular mechanism of specnuezhenide in the treatment of colorectal cancer targeting carboxylesterase
Gut microbiota-based pharmacokinetic-pharmacodynamic study and molecular mechanism of specnuezhenide in the treatment of colorectal cancer targeting carboxylesterase
摘要
关键词
Specnuezhenide/Pharmacokinetics/Tumor/Gut microbiota/Fungi/MetabolismKey words
Specnuezhenide/Pharmacokinetics/Tumor/Gut microbiota/Fungi/Metabolism引用本文复制引用
Hang Yu,Zhao Zhai,Jingyue Wang,Jiandong Jiang,Yan Wang,Hui Xu,Xinyu Yang,Zhengwei Zhang,Jiachun Hu,Jinyue Lu,Jie Fu,Mengmeng Bu,Haojian Zhang..Gut microbiota-based pharmacokinetic-pharmacodynamic study and molecular mechanism of specnuezhenide in the treatment of colorectal cancer targeting carboxylesterase[J].药物分析学报(英文),2023,13(9):1024-1040,17.基金项目
This project was supported by the National Key R&D Program of China(Grant No.:2022YFA0806400),the CAMS Innovation Fund for Medical Sciences(Grant Nos.:2022-I2M-1-028,2022-I2M-2-002,and 2021-I2M-1-007),the National Natural Science Founda-tion of China(Grant Nos.:81973290 and 82173888),and Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD study,China(Grant No.:Z141102004414062).We would like to thank Shimadzu(China)Co.,Ltd.for technological support. (Grant No.:2022YFA0806400)