首页|期刊导航|药物分析学报（英文）|Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis

Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis

Jia-Jia Zhang Ya-Zhou Wang Jian-Li Jiang Ling Li Xiang-Min Yang Zhi-Nan Chen Chang-Geng Song Miao Wang Gai-Qin Zhang Bin Wang Xi Chen Peng Lin Yu-Meng Zhu Zhi-Chuan Sun

药物分析学报（英文）2023，Vol.13Issue(10)：1135-1152,18.

药物分析学报（英文）2023，Vol.13Issue(10)：1135-1152,18.DOI:10.1016/j.jpha.2023.06.008

Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis

Jia-Jia Zhang ¹Ya-Zhou Wang ²Jian-Li Jiang ¹Ling Li ¹Xiang-Min Yang ¹Zhi-Nan Chen ¹Chang-Geng Song ³Miao Wang ¹Gai-Qin Zhang ¹Bin Wang ¹Xi Chen ⁴Peng Lin ¹Yu-Meng Zhu ¹Zhi-Chuan Sun⁵

作者信息

1. National Translational Science Center for Molecular Medicine & Department of Cell Biology,Fourth Military Medical University,Xi'an,710032,China
2. Department of Neurobiology and Institute of Neurosciences,Collaborative Innovation Center for Brain Science,School of Basic Medicine,Fourth Military Medical University,Xi'an,710032,China
3. Department of Neurology,Xijing Hospital,Fourth Military Medical University,Xi'an,710032,China
4. Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education,College of Chemistry and Materials Science,Northwest University,Xi'an,710032,China
5. Department of Neurosurgery,Xi'an Daxing Hospital,Xi'an,710032,China
折叠

摘要

关键词

Morphine tolerance/Mu-opioid receptor/Endocytosis/Monoclonal antibody/Physical dependence

Key words

Morphine tolerance/Mu-opioid receptor/Endocytosis/Monoclonal antibody/Physical dependence

引用本文复制引用

Jia-Jia Zhang,Ya-Zhou Wang,Jian-Li Jiang,Ling Li,Xiang-Min Yang,Zhi-Nan Chen,Chang-Geng Song,Miao Wang,Gai-Qin Zhang,Bin Wang,Xi Chen,Peng Lin,Yu-Meng Zhu,Zhi-Chuan Sun..Monoclonal antibody targeting mu-opioid receptor attenuates morphine tolerance via enhancing morphine-induced receptor endocytosis[J].药物分析学报（英文）,2023,13(10):1135-1152,18.

基金项目

This work was supported by the National Basic Research Pro-gram of China(Grant No.:2015CB553701)and the National Science and Technology Major Project,China(Grant No.:2019ZX09732001). （Grant No.:2015CB553701）

药物分析学报（英文）

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ISSN：2095-1779

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