摘要
Abstract
Objective:To analyze the situation and risk factors of respiratory failure in elderly patients with pulmonary tuberculosis.Methods:Using a retrospective research method,210 elderly pulmonary tuberculosis patients admitted to Liyang People's Hospital in Jiangsu Province from January 2021 to June 2023 were selected as the study subjects.Among them,100 cases with concurrent respiratory failure were selected as the observation group;110 cases without concurrent respiratory failure were selected as the control group.Clinical data of the two groups were collected and compared,including age,gender,disease course,body mass index,smoking history,previous pulmonary disease history,classification of tuberculosis treatment,main clinical symptoms,laboratory test results,imaging test results,etc.Logistic regression model was used to analyze the risk factors of respiratory failure in elderly patients with pulmonary tuberculosis.Results:The proportion of retreated patients in the observation group was 47.0％(47/100),significantly higher than that in the control group's 29.1％(32/110)(x2=7.159,P=0.007);the levels of white blood cell count and procalcitonin were(11.50±2.63)×109/L and(0.71±0.25)μg/L,significantly higher than those in the control group((4.62±2.41)×109/L and(0.29±0.17)μg/L),the differences were statistically significant(t values were 19.782 and 14.347,respectively,both P＜0.001).The serum albumin level in the control group was(31.37±7.56)g/L,significantly higher than that in the observation group((24.61±6.72)g/L)(t=6.821,P＜0.001).Multivariate logistic regression analysis showed that retreated pulmonary tuberculosis(OR(95％CI)=1.262(1.151-1.968)),elevated serum white blood cell count levels(OR(95％CD=2.268(1.278-3.343)),elevated procalcitonin levels(OR(95％CI)=1.751(1.408-3.513)),and decreased serum albumin levels(OR(95％CI)=0.893(0.762-0.969))were independent risk factors for respiratory failure in elderly pulmonary tuberculosis patients.Conclusion:Retreated pulmonary tuberculosis,increased white blood cell count and procalcitonin levels,and decreased serum albumin levels are independent risk factors for respiratory failure in elderly patients with pulmonary tuberculosis.Clinical physicians should be vigilant against these factors and take effective treatment measures to reduce the incidence of respiratory failure in elderly patients with pulmonary tuberculosis.关键词
结核,肺/呼吸障碍/肺通气/老年人/危险因素Key words
Tuberculosis,pulmonary/Respiration disorders/Pulmonary ventilation/Aged/Risk factors分类
医药卫生
