中国康复理论与实践2024，Vol.30Issue(2)：183-188,6.DOI:10.3969/j.issn.1006-9771.2024.02.007
经颅直流电刺激对帕金森病患者认知功能和生活质量影响的Meta分析
Effect of transcranial direct current stimulation on cognitive function and quality of life in patients with Parkin-son's disease:a meta-analysis
摘要
Abstract
Objective To evaluate the effect of transcranial direct current stimulation(tDCS)on the cognitive function and quality of life in patients with Parkinson's disease. Methods Randomized controlled trials(RCTs)on tDCS for Parkinson's disease were searched in PubMed,Web of Sci-ence,Embase,Cochrane Library,CNKI,CBM,VIP and Wanfang Data from the inception to September,2023.Control group was administered standard Parkinson's medications or placebo,physical therapy,and cognitive re-habilitation,while treatment group received tDCS additionally.The quality of the researches was evaluated using the Cochrane Risk of Bias Tool.Data synthesis and analysis were performed using RevMan 5.4 and Stata 17.0,with heterogeneity and sensitivity analyses. Results Eight articles were included.tDCS significantly improved the scores of Montreal Cognitive Assessment(MD = 2.00,95%CI 1.13 to 2.87,P<0.001).However,there was no significant difference in the scores of Parkinson's Disease Questionnaire(MD = 0.73,95%CI-5.78 to 7.23,P = 0.830),Beck Depression Inventory-Ⅱ(MD =-0.77,95%CI-7.14 to 5.60,P = 0.810),and Unified Parkinson Disease Rating Scale-Ⅲ(MD = 1.60,95%CI-0.77 to 3.97,P = 0.190). Conclusion tDCS may improve cognitive function of patients with Parkinson's disease.关键词
帕金森病/认知障碍/经颅直流电刺激/Meta分析Key words
Parkinson's disease/cognitive impairment/transcranial direct current stimulation/meta-analysis分类
医药卫生引用本文复制引用
王铭琛,张文宇,张贤祚,臧万里..经颅直流电刺激对帕金森病患者认知功能和生活质量影响的Meta分析[J].中国康复理论与实践,2024,30(2):183-188,6.基金项目
国家自然科学基金项目(No.82202672) National Natural Science Foundation of China(No.82202672) （No.82202672）
