基于视听觉和运动反馈的脑机接口结合经颅直流电刺激对脑卒中患者上肢功能的效果OA北大核心CSTPCD

Objective To explore the effect of brain-computer interface(BCI)based on visual,auditory and motor feedback com-bined with transcranial direct current stimulation(tDCS)on upper limb function in stroke patients. Methods From March to October,2023,45 stroke inpatients in Xuzhou Rehabilitation Hospital and Xuzhou Central Hospital were divided into BCI group(n = 15),tDCS group(n = 15)and combined group(n = 15)randomly.All the groups received routine rehabilitation,while BCI group received BCI training,tDCS group received tDCS,while the combined group received tDCS and followed by BCI training immediately,for four weeks.They were assessed with Fugl-Meyer Assessment-Upper Extremities(FMA-UE),Action Research Arm Test(ARAT),modi-fied Barthel Index(MBI)and delta-alpha ratio(DAR)and power ratio index(PRI)of electroencephalogram be-fore and after treatment. Results The scores of FMA-UE,ARAT and MBI increased in all the groups after treatment(|t|>5.350,P<0.001),and all these indexes were the best in the combined group(F>3.366,P<0.05);while DAR and PRI decreased in all the groups(|t|>2.208,P<0.05),they were the best in the combined group(F>5.224,P<0.01). Conclusion BCI based on visual,auditory and motor feedback combined with tDCS can further improve the motor func-tion of upper limbs and the activities of daily living of stroke patients.