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子宫颈旁阻滞联合丙泊酚与芬太尼用于宫腔镜手术的临床观察OA

The Clinical Observation on Paracervical Block Combined with Propofol and Fentanyl in Anesthesia for Hysteroscopic Procedure

中文摘要英文摘要

目的:观察子宫颈旁阻滞(PCB)联合丙泊酚与芬太尼用于宫腔镜手术的效果及安全性.方法:选择 120 例拟于 2022 年 2 月—2023 年 6 月在北京市延庆区妇幼保健院接受无插管全麻下宫腔镜手术的女性患者,按照随机数字表法分为子宫颈旁阻滞组(PCB组)和对照组(C组),各 60 例.其中PCB组的麻醉方案是在静脉应用丙泊酚与芬太尼的基础上,加用子宫颈旁利多卡因阻滞,C组的麻醉方案是仅静脉应用丙泊酚与芬太尼,不加用子宫颈旁利多卡因阻滞.观察两组患者在术前、子宫颈扩张及术毕即刻的平均动脉压(MAP)及心率(HR),术中不良事件如高血压、心动过速、心动过缓、体动及呼吸抑制等的发生率,术后麻醉苏醒时间,术后宫缩痛的发生率及疼痛程度,术者对麻醉效果的满意度评分及丙泊酚的总使用量.结果:所有患者均顺利完成手术.C组患者的MAP与HR在子宫扩张及术毕即刻均较PCB组高,差异均有统计学意义(P<0.05);C组患者的MAP与HR在基础值、子宫颈扩张、术毕即刻方面差异有统计学意义(P<0.05).PCB组患者术中高血压、心动过速、体动及呼吸抑制的发生率均低于C组,差异均有统计学意义(P<0.05).PCB组患者术后麻醉苏醒时间短于C组,术后宫缩痛发生率、术后VAS评分均低于C组,丙泊酚使用量少于C组,麻醉效果评分高于C组,差异均有统计学意义(P<0.05).结论:利多卡因子宫颈旁阻滞联合丙泊酚与芬太尼用于宫腔镜手术,具有术中及术后镇痛效果强、循环稳定好、呼吸抑制少、麻醉苏醒快的优势,是一种安全、有效的麻醉方法.

Objective:To observe the efficacy and safety of paracervical block(PCB)combined with Propofol and Fentanyl in hysteroscopic surgery.Method:A total of 120 female patients who were scheduled to undergo hysteroscopic surgery without intubation under general anesthesia(GA)in Yanqing District Maternal and Child Health Hospital of Beijing from February 2022 to June 2023 were selected,according to random number table method,the patients were divided into paracervical block group(PCB group)and control group(C group),with 60 cases each.Among them,the anesthesia regimen of PCB group was based on intravenous application of Propofol and Fentanyl,plus paracervical lidocaine block,while the anesthesia regimen of C group was only intravenous application of Propofol and Fentanyl,without paracervical lidocaine block.The mean arterial pressure(MAP)and heart rate(HR)of patients in the two groups were observed before surgery,after cervical dilation and immediately after surgery,the incidence of intraoperative adverse events such as hypertension,tachycardia,bradycardia,body movement and respiratory depression,the recovery time of anesthesia,the incidence and degree of uterine contraction pain after surgery,the satisfaction score of the operative and the total use of Propofol were observed between the two groups.Result:All patients successfully completed the operation.MAP and HR of patients in C group were higher than those in PCB group at cervical dilation and immediately after surgery,the differences were statistically significant(P<0.05);in C group,there were significant differences in MAP and HR in basic values,cervical dilation,and immediately after surgery(P<0.05).The incidence of intraoperative hypertension,tachycardia,body movement and respiratory depression in PCB group were lower than those in C group,the differences were statistically significant(P<0.05).The postoperative anesthesia recovery time of PCB group was shorter than that of C group,the incidence of postoperative contraction pain and postoperative VAS score were lower than those of C group,the consumption of Propofol was lower than that of C group,and the anesthetic effect score was higher than that of C group,the differences were statistically significant(P<0.05).Conclusion:Lidocaine paracervical block combined with Propofol and Fentanyl for hysteroscopic surgery has the advantages of strong intraoperative and postoperative analgesia,good circulation stability,less respiratory depression,rapid anesthesia recovery,and is a safe and effective anesthesia method.

贺晶

北京市延庆区妇幼保健院麻醉科 北京 102100

利多卡因子宫颈旁阻滞全身麻醉宫腔镜手术

LidocaineParacervical blockGeneral anesthesiaHysteroscopic procedure

《中国医学创新》 2024 (005)

14-19 / 6

10.3969/j.issn.1674-4985.2024.05.004

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