摘要
Abstract
Objective:To explore of the effect of single hole thoracoscopy pneumonectomy in the treatment of early stage lung cancer and its influence on the levels of tumor markers.Method:A total of 116 early stage lung cancer patients admitted to Suzhou Hospital of Traditional Chinese Medicine from July 2020 to December 2022 were selected,they were divided into a single hole group and a two holes group based on the surgical method,with 58 cases in each group.The single hole group underwent single hole thoracoscopic pneumonectomy,while the two holes group underwent two holes thoracoscopic pneumonectomy.The surgical effects,pain scores,tumor marker levels,and incidence of complications were compared between the two groups.Result:There were no statistically significant differences in surgical time and the number of lymph node dissection between the two groups(P>0.05).The intraoperative bleeding volume in the single hole group was less than that in the two holes group,and the postoperative drainage time and hospitalization time were shorter than those in the two holes group,the differences were statistically significant(P<0.05).At 24 hours,3 days,and upon discharge,the pain scores in the single hole group were lower than those in the two holes group,the differences were statistically significant(P<0.05).At 24 h after operation,the soluble cell keratin 19 fragment(Cyfra21-1),carbohydrate antigen 125(CA125)and carcinoembryonic antigen(CEA)in the single hole group were lower than those in the two holes groups,the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion:Compared with two holes thoracoscopic pneumonectomy for the treatment of early stage lung cancer,single hole thoracoscopic pneumonectomy has a better surgical effect,can reduce surgical trauma,alleviate postoperative pain,lower tumor marker levels,promote postoperative recovery,and do not increase the incidence of postoperative complications,it is safe and reliable.关键词
单孔胸腔镜/两孔胸腔镜/早期肺癌/肿瘤标志物Key words
Single hole thoracoscopy/Two holes thoracoscopy/Early stage lung cancer/Tumor markers
