中国医学创新2024，Vol.21Issue(5)：165-169,5.DOI:10.3969/j.issn.1674-4985.2024.05.036
抑郁症发病的脑功能机制研究进展
Research Progress on Brain Function Mechanism of Onset of Depressive Disorder
摘要
Abstract
Depressive disorder is a mental disease caused by many reasons,and its pathogenesis has not been fully defined.This paper summarizes the pathogenesis of depression disorder from the perspective of brain function and structure,and finds that depression disorder is closely related to brain regions such as hippocampus and prefrontal cortex.The decrease in the area and volume of hippocampus and prefrontal cortex and the damage of neuronal morphology and ultrastructure are the anatomical and structural basis of depression disorder.Decreased blood flow,decreased metabolism,abnormal brain network connectivity and imbalance of neuroelectrophysiological activity are the brain functional mechanisms of depression disorder.关键词
抑郁症/神经元/功能连接/结构连接/神经电生理Key words
Depression disorder/Neuron/Functional connectivity/Structural connectivity/Neuroelectrophysiology引用本文复制引用
李芃菲,肖敏,马雪娇,严兴科,马重兵..抑郁症发病的脑功能机制研究进展[J].中国医学创新,2024,21(5):165-169,5.基金项目
国家自然科学基金项目(82360974) （82360974）
甘肃省高校青年博士支持项目(2023QB-088) （2023QB-088）
甘肃中医药大学引进人才科研启动基金立项项目(2023YJRC-01) （2023YJRC-01）
甘肃中医药大学科学研究与创新基金项目(2021KCYB-1) （2021KCYB-1）
