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肠道激素PYY在肥胖和2型糖尿病中的研究进展

郭小佩 刘清泉 刘德胜 郑瑞 陈会

中国医学创新2024,Vol.21Issue(5):180-185,6.
中国医学创新2024,Vol.21Issue(5):180-185,6.DOI:10.3969/j.issn.1674-4985.2024.05.039

肠道激素PYY在肥胖和2型糖尿病中的研究进展

Research Progress of Intestinal Hormone PYY in Obesity and Type 2 Diabetes Mellitus

郭小佩 1刘清泉 2刘德胜 2郑瑞 1陈会2

作者信息

  • 1. 西安医学院 陕西 西安 710021
  • 2. 空军军医大学唐都医院内分泌科 陕西 西安 710038
  • 折叠

摘要

Abstract

Type 2 diabetes mellitus is a chronic metabolic disease on the pathological basis of insulin resistance,accounting for more than 90%of the diabetes population.At present,it has a profound influence in the world,and hundreds of millions of patients suffer from it.Obesity,as one of the important risk factors of type 2 diabetes mellitus,plays an important role in the occurrence,development,treatment and prognosis of diabetes.With the improvement of living standards,the proportion of obese patients with type 2 diabetes mellitus in diabetes population has increased,and the existing treatment methods can not meet the growing demand.Finding new ways to reduce blood sugar and weight has also been put on the agenda to treat type 2 diabetes mellitus,and intestinal hormones have been found to play an important role in weight loss and improvement of islet function,among which peptide YY(PYY)has become a research hotspot in recent years.This article will focus on the intestinal hormone PYY to reduce weight and improve diabetes provides an overview,and provide new ideas for the treatment of type 2 diabetes mellitus.

关键词

2型糖尿病/肥胖/酪酪肽/肠道激素/糖脂代谢紊乱

Key words

Type 2 diabetes mellitus/Obesity/Peptide YY/Intestinal hormones/Disorder of glucose and lipid metabolism

引用本文复制引用

郭小佩,刘清泉,刘德胜,郑瑞,陈会..肠道激素PYY在肥胖和2型糖尿病中的研究进展[J].中国医学创新,2024,21(5):180-185,6.

基金项目

军队保健课题(20BJZ12) (20BJZ12)

中国医学创新

1674-4985

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