中国中医药图书情报杂志2024，Vol.48Issue(2)：41-45,5.DOI:10.3969/j.issn.2095-5707.202308088
基于数据挖掘的外治烧烫伤中药复方专利用药规律研究
Study on the Medication Law of National Patent Compounds of TCM for External Treatment of Burn and Scald
摘要
Abstract
Objective To study the medication law of national patent compounds of TCM for external treatment of burn and scald based on data mining.Methods The website of the State Intellectual Property Office was searched for the data of external TCM compound patents for burn and scald,and Excel 2019,SPSS Modeler 18.0 and SPSS Statistics 25.0 were used to analyze the data on medication frequency,property and taste,meridian,association rules and clustering analysis of screened patent compounds.Results A total of 1 147 patents were included in the study,involving 1 147 prescriptions and 1 325 kinds of Chinese materia medica.There were 42 kinds of high-frequency Chinese materia medica(frequency>50).The main property was cold,the main tastes were bitter,sweet and pungent,and meridians were mainly liver,heart and lung meridians.The maim medicinal categories were medicines of clearing-heat,promoting blood circulation and reducing stasis,and giving astringents to stop bleeding.10 second-order correlation terms and 18 third-order correlation terms were obtained.Coptidis Rhizoma,Scutellariae Radi,Phellodendri Chinensis Cortex and Rhei Radix et Rhizoma were the key drugs in the drug association items.Clustering analysis of high-frequency drugs was divided into 6 categories.Conclusion The national patent compounds for external treatment of burn and scald are mainly composed of drugs such as clearing heat and detoxification,cooling blood and stopping bleeding,activating blood circulation and removing stasis and relieving swelling and pain,etc.Clinically,it can be flexibly applied according to such key drugs.关键词
烧烫伤/中医外治法/数据挖掘/用药规律/国家专利Key words
burn and scald/TCM external treatment/data mining/medication law/national patent分类
医药卫生引用本文复制引用
黎祖鸣,肖瑶,陈雪如,张芷童,李镇南,黄雨欣,卢月,刘娜..基于数据挖掘的外治烧烫伤中药复方专利用药规律研究[J].中国中医药图书情报杂志,2024,48(2):41-45,5.基金项目
中华中医药学会青年人才托举工程项目(2021-QNRC2-B07) （2021-QNRC2-B07）
广州市科技计划项目(202201020317、202102020545) （202201020317、202102020545）
广东省中医院朝阳人才科研专项(ZY2022KY10) （ZY2022KY10）
