中国中医药信息杂志2024，Vol.31Issue(3)：34-41,8.DOI:10.19879/j.cnki.1005-5304.202307011
基于证候-药物的新安医家治疗咳嗽医案数据挖掘研究
Study on Data Mining of Cough Medical Records Treated by Xin'an Doctors Based on Syndrome-drugs
摘要
Abstract
Objective To study the syndrome-drug association rule and the medication law of cough medical cases treated by Xin'an doctors using the data mining method;To provide reference for the treatment of cough.Methods The medical records of Xin'an doctors were collected and summarized.The frequency analysis,topology analysis and Louvain clustering analysis were used to conduct data mining research on syndrome types and prescriptions,and the relationship between syndrome types and prescriptions in cough treatment medical records and the law of drug composition in prescriptions were discussed.Results A total of 525 medical cases were included,and 26 kinds of syndromes were obtained,such as wind-heat invading lung,phlegm-dampness holding lung,lung qi deficiency.There were 243 kinds of Chinese materia medica involved,and 18 kinds of Chinese materia medica were with more than 70 times in frequency.The main properties were cold,warm and mild,and the main tastes were sweet,bitter and pungent,mainly in lung meridian,or the main properties were mild and warm and the main taste was sweet,mainly in spleen and stomach meridian.There were 25 categories in efficacy,which were mainly tonics and heat-clearing medicine.30 core medicines and core medicinal networks were obtained,such as Glycyrrhizae Radix et Rhizoma,Poria and Armeniacae Semen Amarum.The core drug combination of main syndromes of exogenous cough and excess syndrome and deficient syndrome of endogenous cough were obtained by syndrome-drug clustering analysis.Conclusion Xin'an doctors have distinctive characteristics in the diagnosis and treatment of cough diseases,and pay attention to the use of the methods of"strengthening the basic and promoting original qi","nourishing yin and protecting yin","cultivating the soil and promoting gold"and the inheritance of the prescriptions on the basis of cough relieving,phlegm resolving,and syndrome-based treatment.关键词
咳嗽/证候/药物/用药规律/证候规律/核心中药/数据挖掘Key words
cough/syndrome/drug/medication law/syndrome law/core Chinese materia medica/data mining分类
医药卫生引用本文复制引用
王卉,丁焕章,杨勤军,杨程,童佳兵,李泽庚..基于证候-药物的新安医家治疗咳嗽医案数据挖掘研究[J].中国中医药信息杂志,2024,31(3):34-41,8.基金项目
国家自然科学基金区域创新发展联合基金重点支持项目(U20A20398) （U20A20398）
安徽省临床医学研究转化专项(202204295107020045) （202204295107020045）
