吉林医药学院学报2024，Vol.45Issue(2)：101-104,4.
肺腺癌肿瘤标记物的性别差异分析
Gender Difference Analysis of Tumor Markers in Lung Adenocarcinoma
摘要
Abstract
Objective To explore the gender differences of tumor markers in lung adenocarcinoma and provide a relevant basis for precise medical treatment of lung adenocarcinoma.Method From January 1,2020 to January 1,2022,168 patients with lung adenocarcinoma di-agnosed by pathology at the Department of Thoracic Surgery of Yanbian University Affiliated Hospital were collected,including 52 males and 116 females.Tumor markers were measured at the Laboratory of Yanbian University Affiliated Hospital and relevant inpatient medi-cal records were consulted to obtain information.Conduct data analysis based on SPSS 23.0 statistical software.Results The positive rates of male tumor markers ranged from high to low,including cytokeratin 19 fragment(Cyfra21-1),neuron-specific enolase(NSE),gas-trin releasing peptide precursor(ProGRP),carcinoembryonic antigen(CEA),carbohydrate antigen 199(CA199),carbohydrate antigen 125(CA125),and carbohydrate antigen 153(CA153);The positive rates of female tumor markers ranged from high to low,are:NSE,Cy-fra21-1,CA125,ProGRP,CEA,CA199,and CA153;The difference in positive tumor markers between different genders was found in Cy-fra21-1(P<0.05).Conclusion There is a gender difference in Cyfra21-1 among lung adenocarcinoma patients,which can serve as a precise medical reference indicator for lung adenocarcinoma.关键词
肺腺癌/肿瘤标记物/性别差异Key words
lung adenocarcinoma/tumor markers/gender difference分类
医药卫生引用本文复制引用
李犇,车成日,蔡建辉..肺腺癌肿瘤标记物的性别差异分析[J].吉林医药学院学报,2024,45(2):101-104,4.基金项目
国家自然科学基金重大科研仪器研制项目(21827812) （21827812）
