吉林医药学院学报2024，Vol.45Issue(2)：136-139,4.
强直性脊柱炎易感基因的研究进展
Research Progress on Susceptibility Genes of Ankylosing Spondylitis
摘要
Abstract
Ankylosing spondylitis(AS)is an autoimmune disease caused by a combination of genetic,infectious,immune,and environmen-tal factors,among which genetic factors are strongly associated with the onset of AS.At present,the susceptibility genes discovered and the pathogenesis of AS are not very clear.This article reviews the roles of the main histocompatibility complex(MHC)genes related to it,including theHLA-B27 gene,TNF-α gene,and IFN-γ gene,as well as non-MHC genes,including theERAP1 gene and IL-23/IL-17 immune pathway related genes,in the pathogenesis of AS.It is of great significance for further understanding the correlation between sus-ceptibility genes and ankylosing spondylitis.关键词
强直性脊柱炎/易感基因/主要组织相容性复合体Key words
ankylosing spondylitis/susceptible genes/major histocompatibility complex分类
医药卫生引用本文复制引用
姜佳彤,刘天月,武风云,王艺潼,李萌,宋玉国..强直性脊柱炎易感基因的研究进展[J].吉林医药学院学报,2024,45(2):136-139,4.基金项目
吉林省自然科学基金(YDZJ202201ZYTS152) （YDZJ202201ZYTS152）
