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三叉神经痛动物模型的研究现状

何科泰 徐名颉 周昶含 米金龙 李忆博 刘磊

国际口腔医学杂志2024,Vol.51Issue(2):217-226,10.
国际口腔医学杂志2024,Vol.51Issue(2):217-226,10.DOI:10.7518/gjkq.2024014

三叉神经痛动物模型的研究现状

Current status of animal model on trigeminal neuralgia

何科泰 1徐名颉 1周昶含 1米金龙 1李忆博 1刘磊1

作者信息

  • 1. 口腔疾病防治全国重点实验室 国家口腔医学中心 国家口腔疾病临床医学研究中心四川大学华西口腔医院创伤整形外科 成都 610041
  • 折叠

摘要

Abstract

Trigeminal neuralgia is a common clinical disease in stomatology.It is characterized by severe pain like elec-tric shock,thereby seriously affecting the life and work of patients.Trigeminal neuralgia can be divided into three types with different causes and characteristics.Among them,classical trigeminal neuralgia has the main pathogenesis of me-chanical compression,and inflammatory factors also significantly affect this process.Establishing an appropriate animal model of trigeminal neuralgia plays an important role in understanding the etiology and pathogenesis of the disease.Such a model can also serve as the experimental methodological basis for studying the treatment of trigeminal neuralgia.Scho-lars have established various trigeminal neuralgia animal models for different experimental purposes and scenarios.This article reviews the research status of animal experimental models of trigeminal neuralgia.

关键词

三叉神经痛/动物模型/发病机制

Key words

trigeminal neuralgia/animal model/pathogenesis

分类

医药卫生

引用本文复制引用

何科泰,徐名颉,周昶含,米金龙,李忆博,刘磊..三叉神经痛动物模型的研究现状[J].国际口腔医学杂志,2024,51(2):217-226,10.

基金项目

四川省科学技术厅应用基础研究项目(2020YJ0278) Applied Basic Research Programs of Science and Technology Department of Sichuan Province(2020YJ0278) (2020YJ0278)

国际口腔医学杂志

OA北大核心CSTPCD

1673-5749

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