国际口腔医学杂志2024,Vol.51Issue(2):217-226,10.DOI:10.7518/gjkq.2024014
三叉神经痛动物模型的研究现状
Current status of animal model on trigeminal neuralgia
摘要
Abstract
Trigeminal neuralgia is a common clinical disease in stomatology.It is characterized by severe pain like elec-tric shock,thereby seriously affecting the life and work of patients.Trigeminal neuralgia can be divided into three types with different causes and characteristics.Among them,classical trigeminal neuralgia has the main pathogenesis of me-chanical compression,and inflammatory factors also significantly affect this process.Establishing an appropriate animal model of trigeminal neuralgia plays an important role in understanding the etiology and pathogenesis of the disease.Such a model can also serve as the experimental methodological basis for studying the treatment of trigeminal neuralgia.Scho-lars have established various trigeminal neuralgia animal models for different experimental purposes and scenarios.This article reviews the research status of animal experimental models of trigeminal neuralgia.关键词
三叉神经痛/动物模型/发病机制Key words
trigeminal neuralgia/animal model/pathogenesis分类
医药卫生引用本文复制引用
何科泰,徐名颉,周昶含,米金龙,李忆博,刘磊..三叉神经痛动物模型的研究现状[J].国际口腔医学杂志,2024,51(2):217-226,10.基金项目
四川省科学技术厅应用基础研究项目(2020YJ0278) Applied Basic Research Programs of Science and Technology Department of Sichuan Province(2020YJ0278) (2020YJ0278)