陈岩 1陈麟凤 1何欣 1王岩 1于文娟 1刘璇 1刘思琪1
作者信息
- 1. 首都医科大学附属北京世纪坛医院输血科,北京 100038
- 折叠
摘要
Abstract
Objective To investigate the affecting factors of perioperative red blood cell transfusions in patients with colorectal cancer,thus providing evidence for rational use of blood in clinic.Methods Data were collected from January,2013 to January,2020 regarding clinical records,laboratory tests and perioperative blood transfusions of 295 patients in our hospital.The main factors involved in the red blood cell transfusion process,i.e.patient's age,gender,preoperative hemoglobin level,preoperative coagulation,operation time,tumor location,tumor volume,tumor staging,hospital stay were classified and analyzed.Results Of the 295 patients,106(35.9%)had intraoperative blood loss greater than 600 mL,the intraoperative blood transfusion rate being 49.2%.The higher transfusion rate was associated with preoperative anemia(Hb＜100 g/L)in 51.0%of patients.The volume of intraoperatively transfused red blood cells accounted for 52.1%of the blood perioperatively used.Multivariate logistic regression analysis showed the most influential factors that affected the volume of intraoperative red blood cells were patients'age(P＜0.001)and cancer location(P=0.004 for colon cancer;P=0.003 for rectal cancer),which were statistically significant predictors.In terms of the perioperative red blood cell transfusion volume,the significantly associated variable was tumor size(P=0.037).Significant correlation was observed neither between patient age,gender and perioperative blood transfusion(P＞0.05)nor between red blood cell volume and length of hospital stay(inter-operative P=0.428,perioperative P=0.604),surgical incision type(P=0.784),or incision healing(P=0.056).The ratio of red blood cell to plasma infusion was reasonable during the operation,and there was no need for"matched whole blood"infusion.Conclusion The main influencing factors of perioperative blood transfusions are tumor location and size instead of patients'age,sex,preoperative hemoglobin level,operation time and tumor staging.Perioperative blood management is essential to reduce blood transfusion and shorten hospital stay.关键词
结直肠癌/术中输血/围手术期输血/患者血液管理Key words
Colorectal neoplasms/Intraoperative blood transfusion/Perioperative blood transfusion/Patient blood management分类
医药卫生
