南京医科大学学报（自然科学版）2024，Vol.44Issue(3)：380-386,7.DOI:10.7655/NYDXBNSN230852
二维斑点追踪技术联合实时三维超声心动图评价肥胖对原发性高血压患者左房功能的影响
Evaluation of the effect of obesity on left atrial function in patients with essential hypertension using two-dimensional speckle tracking imaging combined with real-time three-dimensional echocardiography
摘要
Abstract
Objective:To evaluate the effect of obesity on left atrial function in patients with essential hypertension by using a combined approach of two-dimensional speckle tracking imaging(2D-STI)and real-time three-dimensional echocardiography(RT-3DE).Methods:A total of 132 patients diagnosed with essential hypertension and 114 controls with normal blood pressure were enrolled from Jiangning Hospital Affiliated to Nanjing Medical University from April 2022 to July 2023.According to the body mass index(BMI),they were stratified into six subgroups.Left atrial longitudinal strain and mechanical function indices were obtained using the combined 2D-STI and RT-3DE techniques to compare differences in left atrial function among the groups.Results:Compared to the healthy control group with the same BMI category,the hypertension group showed a decrease in left atrial reservoir strain(LASr)and left atrial conduit strain(LAScd)(P＜0.05);As BMI increased,LASr,LAScd,total left atrial ejection fraction(LAEFt),passive left atrial positive ejection fraction(LAEFp),and active left atrial ejection fraction(LAEFa)decreased in hypertension patients(P＜0.05),while left atrial contractile strain(LASct)showed no significant difference(P＞0.05).Multivariate linear regression analysis revealed that BMI was independently negatively correlated with LASr,LAScd,LAEFt,LAEFp and LAEFa in the hypertension group,respectively(P＜0.05),while systolic blood pressure showed no significant correlation with left atrial function in hypertensive patients(P＞0.05).Conclusion:Hypertension can lead to the impairment of left atrial function and with an increase in BMI,especially when combined with obesity,the damage to left atrial function may be further exacerbated to a certain extent.关键词
左房功能/二维斑点追踪技术/高血压/肥胖/实时三维超声心动图Key words
left atrial function/two-dimensional speckle tracking imaging/hypertension/obesity/real-time three-dimensional echo-cardiography分类
医药卫生引用本文复制引用
相三婷,王文平,雍永宏,孙伟,张盼盼,童梦佳,陈璐..二维斑点追踪技术联合实时三维超声心动图评价肥胖对原发性高血压患者左房功能的影响[J].南京医科大学学报（自然科学版）,2024,44(3):380-386,7.基金项目
国家自然科学基金(82270362) （82270362）
南京市江宁区科技局惠民发展计划(2022103S) （2022103S）
