实验动物与比较医学2024，Vol.44Issue(1)：105-114,10.DOI:10.12300/j.issn.1674-5817.2023.146
《动物研究:体内实验报告》即ARRIVE 2.0指南的解释和阐述(五)
Interpretation and Elaboration for the ARRIVE Guidelines 2.0-Animal Research:Reporting In Vivo Experiments(Ⅴ)
摘要
Abstract
Improving the reproducibility of biomedical research results is a major challenge.Transparent and accurate reporting of the research process enables readers to evaluate the reliability of the research results and further explore the experiment by repeating it or building upon its findings.The ARRIVE 2.0 guidelines,released in 2019 by the UK National Centre for the Replacement,Refinement and Reduction of Animals in Research(NC3Rs),provide a checklist that is applicable to any in vivo animal research report.These guidelines aim to improve the standardization of experimental design,implementation,and reporting,as well as enhance the reliability,repeatability,and clinical translation of animal experimental results.The use of the ARRIVE 2.0 guidelines not only enriches the details of animal experimental research reports,ensuring that information on animal experimental results is fully evaluated and utilized,but also enables readers to understand the content expressed by the author accurately and clearly,promoting the transparency and completeness of the fundamental research review process.At present,the ARRIVE 2.0 guidelines have been widely adopted by international biomedical journals.This article is based on the best practices following the ARRIVE 2.0 guidelines in international journals,and it interprets,explains,and elaborates in Chinese the fifth part of the comprehensive version of the ARRIVE 2.0 guidelines published in PLoS Biologyin 2020(the original text can be found at https://arriveguidelines.org).This section includes the items 6-11 of Recommended 11 section,covering"Animal Care and Monitoring","Interpretation/Scientific Implications","Generalisability/Translation","Protocol Registration","Data Access"and"Declaration of Interests".Its aim is to promote a comprehensive understanding and use of the ARRIVE 2.0 guidelines among domestic researchers,to enhance the standardization of experimental animal research and reporting,and to promote high-quality development of experimental animal sciences and comparative medicine research in China.关键词
动物实验/ARRIVE 2.0指南/ARRIVE推荐11条/疼痛管理/动物照护和监测Key words
Animal experiment/ARRIVE 2.0 guidelines/ARRIVE Recommended set/Pain management/Animal care and monitoring分类
医药卫生引用本文复制引用
马政文,卢选成,刘永刚,陶雨风,庞万勇,李夏莹,刘晓宇,李垚,王剑,卢今,陈国元,卢晓,白玉..《动物研究:体内实验报告》即ARRIVE 2.0指南的解释和阐述(五)[J].实验动物与比较医学,2024,44(1):105-114,10.基金项目
国家重点研发计划"实验动物共性关键质量评价技术标准研究"(2022YFF0711000) （2022YFF0711000）
中国科学技术期刊编辑学会2023年翰笔计划医学中青年编辑科研项目"动物实验医学研究及报告规范化的国际对标(指南汉化推广)"(HBJH-2023-A16) （指南汉化推广）
