四川精神卫生2024，Vol.37Issue(1)：16-20,5.DOI:10.11886/scjsws20231113005
重复经颅磁刺激治疗慢性失眠障碍的效果及影响因素
Efficacy and influencing factors of repetitive transcranial magnetic stimulation in the treatment of chronic insomnia
摘要
Abstract
Background Chronic insomnia is characterized by a prolonged and recurrent course.The efficacy of repeated transcranial magnetic stimulation(rTMS)as a physical therapy method to improve sleep quality remains inadequately supported by evidence,particularly regarding its relationship with personality traits.Objective To explore the efficacy and influencing factors of rTMS in the treatment of chronic insomnia,and to provide insights into its therapeutic potential.Method A total of 46 patients who met the diagnostic criteria for chronic insomnia according to the Diagnostic and Statistical Manual of Mental Disorders,fifth edition(DSM-5),and were treated at the Third Hospital of Mianyang from September 2022 to September 2023 were selected.Prior to treatment,participants underwent assessments using the Eysenck Personality Questionnaire(EPQ),Hamilton Depression Scale-17 item(HAMD-17)and Hamilton Anxiety Scale(HAMA).The Pittsburgh Sleep Quality Index(PSQI)was used to assess sleep quality before treatment,at the end of the second week of treatment and one week post-treatment.Results At the end of the second week of treatment,patients exhibited significantly improved total PSQI score and subscale scores related to subjective sleep quality,sleep latency,sleep duration,sleep efficiency,sleep disturbance and daytime dysfunction(t=4.755～13.361,P<0.01),with 24 cases(54.35％)showing effective treatment outcomes.Multiple linear regression analysis showed that introverted and extroverted personality traits contributed significantly to the regression equation(B=0.317,P<0.01),explaining 29.90％of the total variation(R2=0.299).Conclusion rTMS treatment may effectively improve the sleep quality of patients with chronic insomnia,with its therapeutic effect appearing to associated with introverted and extroverted personality traits.关键词
重复经颅磁刺激/失眠/人格特征Key words
repetitive Transcranial Magnetic Stimulation/Insomnia/Personality trait分类
临床医学引用本文复制引用
陈晓娅,何佳蔚,刘妍,王怡,姚静,黄晓琦..重复经颅磁刺激治疗慢性失眠障碍的效果及影响因素[J].四川精神卫生,2024,37(1):16-20,5.基金项目
国家自然科学基金项目(项目名称:基于同步TMS-MRI技术研究神经调控治疗抑郁症的脑机制,项目编号:82372080)Funded by National Natural Science Project of China(number,82372080) （项目名称:基于同步TMS-MRI技术研究神经调控治疗抑郁症的脑机制,项目编号:82372080）
