摘要
Abstract
Short stature in puberty significantly affects the physical and mental health of adolescents.The continuous acceleration of skeletal maturation,caused by sex hormones during puberty,limits the time available for growth and poses a considerable challenge for the treatment of short stature.To date,there is still no standardized treatment protocol for this disorder.However,puberty is the last period to improve the final adult height.Currently,commonly used pharmacological treatments in clinical settings include recombinant human growth hormone,gonadotropin-releasing hormone analogs,and third-generation aromatase inhibitors.In recent years,personalized treatment aiming to improve the final adult height has become a key focus in clinical practice.This article provides a comprehensive summary of research on pharmacological therapies for height improvement in pubertal children with short stature,offering valuable insights for healthcare professionals.[Chinese Journal of Contemporary Pediatrics,2024,26(2):118-123]关键词
矮身材/重组人生长激素/促性腺激素释放激素类似物/芳香化酶抑制剂/青春期Key words
Short stature/Recombinant human growth hormone/Gonadotropin-releasing hormone analog/Aromatase inhibitor/Puberty
