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氧化应激在注意缺陷多动障碍发病机制中的研究进展

吴晨蕾 王孟飞 周荣易

中国当代儿科杂志2024,Vol.26Issue(2):201-206,6.
中国当代儿科杂志2024,Vol.26Issue(2):201-206,6.DOI:10.7499/j.issn.1008-8830.2309039

氧化应激在注意缺陷多动障碍发病机制中的研究进展

Recent research on the role of oxidative stress in the pathogenesis of attention deficit hyperactivity disorder

吴晨蕾 1王孟飞 1周荣易1

作者信息

  • 1. 河南中医药大学第一附属医院儿科医院,河南郑州 450000||河南中医药大学儿科医学院,河南郑州 450000
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摘要

Abstract

Attention deficit hyperactivity disorder(ADHD)is a common neurodevelopmental disorder in children and adolescents,and its etiology and pathogenesis are still unclear.Brain is the organ with the largest oxygen consumption in human body and is easily affected by oxidative imbalance.Oxidative stress has become the key research direction for the pathogenesis of ADHD,but there is still a lack of relevant studies in China.Based on the latest research findings in China and overseas,this article reviews the clinical and experimental studies on oxidative stress in ADHD and explores the association of oxidative stress with neurotransmitter imbalance,neuroinflammation,and cell apoptosis in the pathogenesis of ADHD,so as to provide new research ideas for exploring the pathogenesis of ADHD.[Chinese Journal of Contemporary Pediatrics,2024,26(2):201-206]

关键词

注意缺陷多动障碍/氧化应激/神经递质/神经炎症/细胞凋亡

Key words

Attention deficit hyperactivity disorder/Oxidative stress/Neurotransmitter/Neuroinflammation/Cell apoptosis

引用本文复制引用

吴晨蕾,王孟飞,周荣易..氧化应激在注意缺陷多动障碍发病机制中的研究进展[J].中国当代儿科杂志,2024,26(2):201-206,6.

基金项目

国家自然科学基金(82104928) (82104928)

中国博士后科学基金第70批面上项目(2021M701123). (2021M701123)

中国当代儿科杂志

OA北大核心CSTPCDMEDLINE

1008-8830

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