中国当代儿科杂志2024,Vol.26Issue(2):201-206,6.DOI:10.7499/j.issn.1008-8830.2309039
氧化应激在注意缺陷多动障碍发病机制中的研究进展
Recent research on the role of oxidative stress in the pathogenesis of attention deficit hyperactivity disorder
摘要
Abstract
Attention deficit hyperactivity disorder(ADHD)is a common neurodevelopmental disorder in children and adolescents,and its etiology and pathogenesis are still unclear.Brain is the organ with the largest oxygen consumption in human body and is easily affected by oxidative imbalance.Oxidative stress has become the key research direction for the pathogenesis of ADHD,but there is still a lack of relevant studies in China.Based on the latest research findings in China and overseas,this article reviews the clinical and experimental studies on oxidative stress in ADHD and explores the association of oxidative stress with neurotransmitter imbalance,neuroinflammation,and cell apoptosis in the pathogenesis of ADHD,so as to provide new research ideas for exploring the pathogenesis of ADHD.[Chinese Journal of Contemporary Pediatrics,2024,26(2):201-206]关键词
注意缺陷多动障碍/氧化应激/神经递质/神经炎症/细胞凋亡Key words
Attention deficit hyperactivity disorder/Oxidative stress/Neurotransmitter/Neuroinflammation/Cell apoptosis引用本文复制引用
吴晨蕾,王孟飞,周荣易..氧化应激在注意缺陷多动障碍发病机制中的研究进展[J].中国当代儿科杂志,2024,26(2):201-206,6.基金项目
国家自然科学基金(82104928) (82104928)
中国博士后科学基金第70批面上项目(2021M701123). (2021M701123)