中国肺癌杂志2024，Vol.27Issue(2)：126-132,7.DOI:10.3779/j.issn.1009-3419.2023.106.29
肿瘤代谢标志物在肺癌液体活检中的研究进展
Research Progress on Tumor Metabolic Biomarkers in Liquid Biopsy of Lung Cancer
邹诗施 1李宁 1张天宇 1耿庆1
作者信息
- 1. 430060 武汉,武汉大学人民医院胸外科
- 折叠
摘要
Abstract
Liquid biopsy is gradually being applied in the clinical diagnosis and treatment of lung cancer.At pres-ent,with the development of metabolomics,more and more metabolic biomarkers are considered as potential sensitive mark-ers reflecting the occurrence and development of tumors.This article summarizes the changes in the main metabolic pathways of lung cancer,including glucose metabolism,amino acid metabolism,lipid metabolism,sphingolipid metabolism,glycero-phospholipid metabolism,and purine metabolism.Meanwhile,this article reviews the role of metabolic biomarkers in the early diagnosis of lung cancer,predicting disease progression,and evaluating the efficacy of chemotherapy and immunotherapy,aim-ing to provide effective biomarkers for tumor diagnosis and treatment.关键词
肺肿瘤/代谢标志物/液体活检/代谢组学Key words
Lung neoplasms/Metabolic biomarker/Liquid biopsy/Metabolomics引用本文复制引用
邹诗施,李宁,张天宇,耿庆..肿瘤代谢标志物在肺癌液体活检中的研究进展[J].中国肺癌杂志,2024,27(2):126-132,7.
