中国实用儿科杂志2024，Vol.39Issue(2)：135-139,5.DOI:10.19538/j.ek2024020612
西安市先天性甲状腺功能减退症流行病学特征及影响因素分析
Epidemiological features and influencing factors for congenital hypothyroidism in Xi'an
摘要
Abstract
Objective To study the epidemiological characteristics and risk factors of congenital hypothyroidism(CH)in Xi'an,and to provide evidence for making intervention strategies.Methods From January 1,2020 to December 31,2021,the screening data for neonatal CH at the Xi'an Neonatal Disease Screening Center were gathered.The case group and the control group's fundamental data,clinical characteristics,and other related data were analyzed using univariate analysis by the case-control study technique.From the univariate analysis,a few factors that were statistically different were chosen and were inclucled in the multivariate Logistic regression equation analysis.Results Between 2020 and 2021,148250 newborns were screened for CH;104 of them were found to have the disease.Multiple Logistic regression analysis revealed that long period of pregnancy,high educational level of mothers,and birth weight being 2.5～4 kg were protective factors of CH(P＜0.05),while the risk factors were birth season being winter,maternal thyroid diseases during pregnancy,mother's advancedage,multiple pregnanay or delivery and cesarean section.Conclution The incidence rate of CH in Xi'an is basically the same as that in China's iodine-sufficient regions.The CH screening rate in Xi'an has steadily increased in recent years.It is advised that women of childbearing age get ready for pregnancy and receive prenatal care to improve population quality since maternal personal variables and environmental factors affect the etiology of neonatal CH.关键词
先天性甲状腺功能减退症/新生儿疾病筛查/促甲状腺激素Key words
congenital hypothyroidism/neonatal disease screening/thyroid stimulating hormone分类
医药卫生引用本文复制引用
闫莹玉,何玉莹,孟祥萍,杨小艳,尤嘉,万星琦,郑晶晶,周扬,陈艳妮..西安市先天性甲状腺功能减退症流行病学特征及影响因素分析[J].中国实用儿科杂志,2024,39(2):135-139,5.基金项目
西安市卫生健康委员会一般研究项目(2021yb28) （2021yb28）
