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基因治疗的双重考察OACSTPCD

Double investigation of gene therapy

中文摘要英文摘要

从生物学上看,基因是人之为人的关键.随着人类对基因技术的不断推进,基因治疗成为当前生命科学领域极富活力也面临巨大争议的前沿话题:在给人类带来更多疾病治愈希望的同时,它也引发了诸多伦理争论.整理了基因治疗所面临的伦理质疑,从中提炼出个人权利、社会公平、自然秩序等多个方面所受到的挑战,并一一进行回应,由此说明基因治疗的开展在原则上并不违背这些伦理价值.然而,基因编辑事件的发生,为我们敲响警钟:基因治疗的实施边界究竟应在何处?通过对基因编辑事件与"柏林病人"案件的对比分析指出:技术安全层面的考察才是基因治疗安全应用于临床应用的关键所在.

From the biological point of view,genes are the key to being human.With the continuous advancement of human gene technology,gene therapy has become a frontier topic with great vitality and controversy in the field of life science:it has brought more hope for the cure of diseases to human beings,but it has also triggered many ethical debates.This paper sorts out the ethical questions faced by gene therapy,extracts the challenges faced by individual rights,social justice,natural order and so on,and responds one by one,which shows that the development of gene therapy does not violate these ethical values in principle.However,the occurrence of gene editing events has sounded the alarm for us:where should the implementation boundary of gene therapy be?Through the comparative analysis of the gene editing incident and the Berlin patient case,the article points out that the study of technical safety is the key to safe application of gene therapy in clinical applications.

丁敏;虞法

湖南大学马克思主义学院,湖南 长沙 410082

基因治疗伦理审查技术安全"柏林病人"案

gene therapyethical reviewtechnical safety"Berlin patient"case

《中国医学伦理学》 2024 (002)

138-144 / 7

湖南省社会科学成果评审委员会项目"免责性无知条件研究"(XSP20YBC404)

10.12026/j.issn.1001-8565.2024.02.03

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