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医学遗传学检测临床应用及伦理研究综述OACSTPCD

A review of clinical application and ethical research on medical genetic testing

中文摘要英文摘要

医学遗传学检测的伦理问题是生命科学领域十分关注且具有争议的问题之一.随着基因组学研究的快速发展,增加了基因检测用于临床事件进行疾病风险评估的可能性,尤其在精准医疗基因检测及预防检测等方面应用广泛.通过对基因检测临床应用现状及常见伦理问题进行综述,并对相应的伦理原则进行梳理,提出平等尊重、知情同意、隐私保护及不伤害伦理原则,旨在帮助医务工作者规范诊疗行为及增强基因检测伦理方面的意识,促进基因组学研究更好发展.

The ethical issue of medical genetic testing is one of the highly concerned and controversial issues in the field of life sciences.With the rapid development of genomics research,the possibility of using genetic testing for disease risk assessment in clinical events has been increased,especially in precision medical genetic testing and preventive testing.By reviewing the current status and common ethical issues of the clinical application of genetic testing,and sorting out the corresponding ethical principles,this paper proposed the ethical principles of equal respect,informed consent,privacy protection,and non-harm,aiming to help medical staff to regulate diagnosis and treatment behavior,enhance their awareness of the ethical aspects of genetic testing,as well as promote the better development of genomics research.

邓静;王玲;刘帆

四川大学华西护理学院/四川大学华西第二医院妇科护理单元/出生缺陷与相关妇儿疾病教育部重点实验室,四川 成都 610066四川大学华西第二医院/出生缺陷与相关妇儿疾病教育部重点实验室,四川 成都 610066四川大学华西护理学院/口腔疾病研究国家重点实验室/国家口腔疾病临床医学研究中心/四川大学华西口腔医院,四川 成都 610066

医学遗传学基因检测医学伦理学伦理原则

medical geneticsgenetic testingmedical ethicsethical principle

《中国医学伦理学》 2024 (002)

145-151 / 7

10.12026/j.issn.1001-8565.2024.02.04

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