中华神经创伤外科电子杂志2023，Vol.9Issue(6)：338-342,5.DOI:10.3877/cma.j.issn.2095-9141.2023.06.004
重型颅脑损伤合并应激性高血糖患者血糖水平与预后的关系
Relationship between blood glucose level and outcome of severe traumatic brain injury patients with stress hyperglycemia
摘要
Abstract
Objective To explore the relationship between the random blood glucose level and the outcome of severe traumatic brain injury(sTBI)patients with stress hyperglycemia during hospitalization.Methods The in-hospital medical records of 85 patients with sTBI and first-admission random blood glucose＞11.1 mmol/L admitted to the Neurosurgical Intensive Care Unit of the First Affiliated Hospital of Air Force Military Medical University from October 2013 to June 2022 were retrospectively analyzed.Patients were divided into good outcome group(GOS＞3 score)and poor outcome group(GOS≤3 score)according to their GOS score at discharge.The general information of two groups was compared,the multivariate Logistic regression analysis was used to identify risk factors affecting patient prognosis,and the relationship between random blood glucose levels during hospitalization and prognosis was analyzed.Results Of the 85 patients included,67 had poor outcome and 18 had good outcome.The difference in random blood glucose levels between the two groups during hospitalization was statistically significant(P＜0.05),and blood glucose＞11.1 mmol/L was an independent risk factor for the prognosis of sTBI patients.During hospitalization,26 patients developed concurrent infections,including 3 in the group with good outcome and 23 in the group with poor outcome,there was no statistically significant difference in infection rates between the two groups(P＞0.05).Patients with random blood glucose＞11.1 mmol/L had significantly higher infection rates compared to those with ≤11.1 mmol/L,but the differences were not statistically significant(P＞0.05).Conclusion Randomized blood glucose levels during hospitalization in patients with sTBI and SH are associated with prognosis,and blood glucose levels＞11.1 mmol/L are independent risk factors for the prognosis of sTBI patients.关键词
重型颅脑损伤/二次脑损伤/应激性高血糖/预后Key words
Severe traumatic brain injury/Secondary brain injury/Stress-induced hyperglycemia/Prognosis引用本文复制引用
吕伟豪,费晓炜,武秀权,何鑫,郇宇,吴霜,豆雅楠,费舟,胡世颉..重型颅脑损伤合并应激性高血糖患者血糖水平与预后的关系[J].中华神经创伤外科电子杂志,2023,9(6):338-342,5.基金项目
Major Military Logistics Research Project(A WS15J001) （A WS15J001）
Shaanxi Provincial Natural Science Foundation General Project(2020JM-322) （2020JM-322）
Medical Clinical Application Research Project of Xijing Hospital(JSYXM32) （JSYXM32）
Xijing Hospital Discipline Promotion Program(XJZT19ML39)军队后勤科研重大项目(AWS15J001) （XJZT19ML39）
陕西省自然科学基金面上项目(2020JM-322) （2020JM-322）
西京医院医学临床应用研究课题项目(JSYXM32) （JSYXM32）
西京医院学科助推计划(XJZT19ML39) （XJZT19ML39）
