中华脑科疾病与康复杂志(电子版)2023,Vol.13Issue(6):327-334,8.DOI:10.3877/cma.j.issn.2095-123X.2023.06.002
重复经颅磁刺激对脑瘫患儿运动功能康复效果的Meta分析
Effect of repetitive transcranial magnetic stimulation on motor function in children with cerebral palsy:a Meta-analysis
摘要
Abstract
Objective To systematically evaluate the efficacy of repetitive transcranial magnetic stimulation(rTMS)on the rehabilitation of motor function in children with cerebral palsy.Methods Computer searches of Cochrane Library,PubMed,Web of Science,Google Scholar,China Biomedical Database,China Knowledge Network,Wipro Journal Database,Wanfang Database were conducted to screen randomised controlled trials on rTMS for improvement of motor function in children with cerebral palsy with a timeframe of the search from library construction to October 2022.The quality of the included literature was evaluated according to the Cochrane Handbook for Systematic Evaluation and The Physiotherapy Evidence Database scale,and Meta-analysis,subgroup analysis,sensitivity analysis,and publication bias analysis were performed using RevMan5.4.Results Seventeen papers with 1283 patients were finally included.rTMS significantly improved the Gross motor function measure-88 scores(MD=6.74,95%CI:5.26-8.21,P<0.05)and ankle mobility scores(MD=3.38,95%CI:2.87-3.89,P<0.05),developmental quotient(DQ)score(MD=5.62,95%CI:1.62-9.61,P<0.05),but fine motor function measure score(MD=2.21,95%CI:-0.46-4.89,P>0.05)was not significant.The risk of bias was low when GMGM-88 was used as an indicator.Conclusion rTMS is effective in improving gross motor function and DQ in children with cerebral palsy.关键词
脑瘫/重复经颅磁刺激/运动功能/儿童Key words
Cerebral palsy/Repetitive transcranial magnetic stimulation/Motor function/Children引用本文复制引用
杨钰琳,常万鹏,丁江涛,徐红莉,仵宵,肖伯恒,马丽虹..重复经颅磁刺激对脑瘫患儿运动功能康复效果的Meta分析[J].中华脑科疾病与康复杂志(电子版),2023,13(6):327-334,8.基金项目
The Research Planning Project of Higher Medical Education Research Center of Shandong Province 山东省高等医学教育研究中心科研规划课题 ()